1. 天然产物
  2. 疾病研究领域 植物 萜类
  3. 毛茛科 癌症 三萜
  4. 白头翁
  5. Pulchinenoside E2

Pulchinenoside E2  (Synonyms: 白头翁皂苷E2)

目录号: HY-N8098
产品使用指南

Pulchinenoside E2 (Compound 8) 是从 Pulsatilla chinensis 的根中分离出的三萜皂苷。Pulchinenoside E2 对 HL-60 白血病细胞具有细胞毒性,IC50 值为 2.6 µg/mL。

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Pulchinenoside E2 Chemical Structure

Pulchinenoside E2 Chemical Structure

CAS No. : 244202-36-6

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Pulchinenoside E2 (Compound 8) is a triterpene saponin isolated from the roots of Pulsatilla chinensis. Pulchinenoside E2 shows cytotoxic to HL-60 cells with an IC50 value of 2.6 µg/mL[1].

细胞效力
(Cellular Effect)
Cell Line Type Value Description References
A-375 IC50
5.9 μM
Compound: 9
Cytotoxicity against human A375 cells after 72 hrs by sulforhodamine B assay
Cytotoxicity against human A375 cells after 72 hrs by sulforhodamine B assay
[PMID: 23639650]
A549 IC50
7.9 μM
Compound: 9
Cytotoxicity against human A549 cells after 72 hrs by sulforhodamine B assay
Cytotoxicity against human A549 cells after 72 hrs by sulforhodamine B assay
[PMID: 23639650]
HL-60 IC50
2.6 μg/mL
Compound: 8
Cytotoxicity against human HL-60 cells after 72 hrs by MTT assay
Cytotoxicity against human HL-60 cells after 72 hrs by MTT assay
[PMID: 10514313]
HL-60 IC50
3.5 μM
Compound: 9
Cytotoxicity against human HL60 cells after 72 hrs by MTT assay
Cytotoxicity against human HL60 cells after 72 hrs by MTT assay
[PMID: 23639650]
分子量

1059.24

Formula

C53H86O21

CAS 号
中文名称

白头翁皂苷E2

结构分类
初始来源
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
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质量   浓度   体积   分子量 *
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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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