2. Membrane Transporter/Ion Channel Neuronal Signaling Anti-infection
  3. nAChR Parasite Antibiotic
  4. Pyrantel

Pyrantel 是一种口服有效的驱虫剂，也是烟碱乙酰胆碱受体 (nAChR) 激动剂。Pyrantel 可引起寄生虫的痉挛性肌肉麻痹。Pyrantel 可用于寄生虫感染的研究，比如蛔虫病、钩虫感染、肠虫病 (蛲虫感染)、毛霉菌病和旋毛虫病。

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Pyrantel Chemical Structure

Pyrantel Chemical Structure

CAS No. : 15686-83-6

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Pyrantel 的其他形式现货产品:

Customer Review

Other Forms of Pyrantel:

Pyrantel 相关抗体

Top Publications Citing Use of Products

查看 Parasite 亚型特异性产品:

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Amebae Coccidia Leishmania Mite Plasmodium Toxoplasma Trypanosoma Schistosome

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Pyrantel is an orally active anthelmintic and an agonist of the nicotinic acetylcholine receptor (nAChR). Pyrantel can cause spasmodic muscle paralysis in parasites. Pyrantel can be used in the study of parasitic infections such as ascariasis, hookworm infections, intestinal worms (pinworm infections), trichinosis and trichinosis[1][2].

IC50 & Target

Parasites[1][2].
体外研究
(In Vitro)

Pyrantel (10 nM-10 µM; 72 h) shows good anti-A. suum and (0-168.2 M; 72 h) anti-N. americanus activity[1][2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Pyrantel 相关抗体:

Cell Viability Assay[1]

Cell Line: A. suum
Concentration: 10 nM-10 µM
Incubation Time: 72 h
Result: Inhibited A. suum with a pEC50 value of 7.24.

Cell Viability Assay[2]

Cell Line: N. americanus
Concentration: 0-168.2 M (0-100 µg/mL)
Incubation Time: 72 h
Result: Inhibited third-stage larvae and adult of N. americanus with IC50 values of 2.0 and 7.6 mg/mL, respectively.
体内研究
(In Vivo)

Pyrantel (10 mg/kg; p.o.; single) reduces the worms in A. ceylanicum-infected hamsters, with the worm burden reduction of 87.2% and worm expulsion rate of 63.4%[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Male Syrian Golden hamsters (3-week-old; A. ceylanicum-infected)[2].
Dosage: 10 mg/kg
Administration: Oral administration; single.
Result: Exhibited worm burden reduction and worm expulsion rates of 87.2% and 63.4%, respectively.
Clinical Trial
分子量

206.31

Formula

C11H14N2S
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Pyrantel 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Pyrantel15686-83-6nAChRParasiteAntibioticNicotinic acetylcholine receptorsparasitic infectionascariasishookwormpinwormtrichinosisInhibitorinhibitorinhibit

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