2. Anti-infection
  3. Parasite
  4. Pyronaridine

Pyronaridine  (Synonyms: 咯萘啶)

目录号: HY-14749
产品使用指南

摩尔计算器

Pyronaridine 是一种具有口服活性的、含甘露醇的抗疟疾试剂。Pyronaridine 对 P. falciparum 和 Echinococcus granulosus 均具有抗感染活性。

在相同的摩尔浓度下，化合物盐形式与游离形式有相同的生物活性，但盐形式 Pyronaridine tetraphosphate 通常具有更好的水溶性和稳定性。

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Pyronaridine Chemical Structure

Pyronaridine Chemical Structure

CAS No. : 74847-35-1

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Pyronaridine 的其他形式现货产品:

Customer Review

Other Forms of Pyronaridine:

Pyronaridine 相关抗体

Top Publications Citing Use of Products

MCE 顾客使用本产品发表的 2 篇科研文献

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Amebae Coccidia Leishmania Mite Plasmodium Toxoplasma Trypanosoma Schistosome

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Pyronaridine is an orally active Mannich base anti-malarial agent. Pyronaridine is active against P. falciparum and Echinococcus granulosus infection[1][2].

体外研究
(In Vitro)

Pyronaridine (24 h) shows anti-P. falciparum activity with an IC50 value of 1.53-3.94 nM[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Pyronaridine 相关抗体:
体内研究
(In Vivo)

Pyronaridine (57 mg/kg, oral administration, q.d. for 30 days) reduces the parasitic burden in the Echinococcus granulosus-infected mice[2].
Pyronaridine (57 mg/kg, intraperitoneal injection, q.d. for 3 days) reduces the parasitic burden in secondarily infected (cysts) mice[2].
Pyronaridine (57 mg/kg, intraperitoneal injection, for a single dose) exhibits a higher exposure in the liver than in the plasma in male ICR mice[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Echinococcus granulosus-infected mice model[2]
Dosage: 57 mg/kg
Administration: Oral administration, q.d. for 30 days
Result: Reduced 42.4% of parasite wet weight and killed 90.7% of secondary infection (cysts) of E. granulosus ss.
Clinical Trial
分子量

518.05

Formula

C29H32ClN5O2
CAS 号
中文名称

咯萘啶
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Pyronaridine 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Pyronaridine74847-35-1咯萘啶ParasiteArtesunatemalariadrug resistantcystCEechinococcosisinfectionInhibitorinhibitorinhibit

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