1. Others Metabolic Enzyme/Protease
  2. Isotope-Labeled Compounds Phospholipase
  3. (R)-Bromoenol lactone-d7

(R)-Bromoenol lactone-d7  (Synonyms: (R,E)-Bromoenol lactone-d7)

目录号: HY-117068S
产品使用指南

(R)-Bromoenol lactone-d7 ((R,E)-Bromoenol lactone-d7) 是氘代标记的 (R)-Bromoenol lactone。(R)-Bromoenol lactone ((R)-BEL) 是一种不可逆、手性、基于机理的钙非依赖性磷脂酶 γ (iPLA2γ) 抑制剂。(R)-BEL 以约 0.6 μM 的 IC50 抑制人重组 iPLA2γ。

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(R)-Bromoenol lactone-d<sub>7</sub> Chemical Structure

(R)-Bromoenol lactone-d7 Chemical Structure

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  • 参考文献

生物活性

(R)-Bromoenol lactone-d7 ((R,E)-Bromoenol lactone-d7) is deuterium labeled (R)-Bromoenol lactone. (R)-Bromoenol lactone ((R)-BEL) is an irreversible, chiral, mechanism-based inhibitor of calcium-independent phospholipase γ (iPLA2γ). (R)-BEL inhibits human recombinant iPLA2γ with an IC50 of approximately 0.6 μM[1][2].

分子量

324.22

Formula

C16H6D7BrO2

非标记 CAS

478288-90-3

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
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  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
(R)-Bromoenol lactone-d7
目录号:
HY-117068S
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