1. GPCR/G Protein Neuronal Signaling
  2. Adrenergic Receptor
  3. R-(-)-Oxaprotiline

R-(-)-Oxaprotiline  (Synonyms: Levoprotiline)

目录号: HY-122300B
产品使用指南

R-(-)-Oxaprotiline (Levoprotiline)是一种抗抑郁剂,具有抗胆碱能和兴奋交感神经的活性。R-(-)-Oxaprotiline与其对映体C 49802 B-Ba相比,在阻止去甲肾上腺素摄取和抗胆碱能活性方面表现出不同的能力。R-(-)-Oxaprotiline在对人类的研究中显示出与动物实验结果一致的生理作用。R-(-)-Oxaprotiline的使用可以导致心率和动脉血压的适度增加。R-(-)-Oxaprotiline的唾液分泌受到抑制,这与其抗胆碱能特性相符。R-(-)-Oxaprotiline与育成的抗抑郁化合物Levoprotiline的效果相似并且具有较短的起效潜伏期。

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R-(-)-Oxaprotiline Chemical Structure

R-(-)-Oxaprotiline Chemical Structure

CAS No. : 76496-68-9

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生物活性

R-(-)-Oxaprotiline (Levoprotiline) is an antidepressant with anticholinergic and sympathostimulatory activities. R-(-)-Oxaprotiline exhibits different abilities to block norepinephrine uptake and anticholinergic activity compared to its enantiomer C 49802 B-Ba. R-(-)-Oxaprotiline in human studies shows physiological effects consistent with those in animals. Administration of R-(-)-Oxaprotiline results in a modest increase in heart rate and arterial blood pressure. Salivation is inhibited with R-(-)-Oxaprotiline, consistent with its anticholinergic properties. R-(-)-Oxaprotiline has similar effects to the established antidepressant compound Levoprotiline and has a shorter onset of action[1].

分子量

293.40

Formula

C20H23NO

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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R-(-)-Oxaprotiline
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HY-122300B
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