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  3. APLP-1 蛋白, Human (171a.a, HEK293, His)

APLP-1 蛋白, Human (171a.a, HEK293, His)

目录号: HY-P7502
产品使用指南

APLP-1 蛋白, Human (171a.a, HEK293, His)也称作APLP1,在暴露于Mn 的模型中,其在额叶皮质的神经元中含量明显上升。

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描述

APLP-1 Protein, Human (171a.a, HEK293, His), also known as APLP1, is increased in the frontal cortex of Mn-exposed models.

研究背景

人类 APLP-1 基因已被定位到 19 号染色体长臂上,该区域包含晚发家族性 AD 基因座。APLP1 是淀粉样蛋白前体家族的成员。APLP1 表达增加并揭示了淀粉样蛋白-β 弥漫性斑块的存在。

种属

Human

表达系统

HEK293

标签

C-6*His

蛋白编号

P51693 (G42-P212)

基因 ID

333  [NCBI]

蛋白结构
N-term
APLP-1 (G42-P212)
Accession # P51693
6*His
C-term
中文名
重组人淀粉样蛋白 1,His (HEK 293表达)
同用名
rHuAmyloid-like Protein 1, His; APLP-1; Amyloid-like Protein 1
氨基酸序列

GGSPGAAEAPGSAQVAGLCGRLTLHRDLRTGRWEPDPQRSRRCLRDPQRVLEYCRQMYPELQIARVEQATQAIPMERWCGGSRSGSCAHPHHQVVPFRCLPGEFVSEALLVPEGCRFLHQERMDQCESSTRRHQEAQEACSSQGLILHGSGMLLPCGSDRFRGVEYVCCPPHHHHHH

分子量

18-20 kDa

纯度

Greater than 80% as determined by reducing SDS-PAGE.

内毒素含量

<1 EU/μg, determined by LAL method.

文件资料
参考文献

APLP-1 Protein, Human (171a.a, HEK293, His) 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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APLP-1 Protein, Human (171a.a, HEK293, His)
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HY-P7502
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