Angiogenin 蛋白, Human

Angiogenin Protein, Human is a potent inducer of new blood vessel formation. Angiogenin may contribute to the malignant transformation of gliomas as well as to angiogenic processes.

血管生成素（Ang）是胰腺核糖核酸酶（RNase）超家族的成员之一，具有不寻常的生物学特性。血管生成素的氨基酸序列显示，它与RNase A同源。它与牛酶具有33%的序列同一性，包括构成催化活性位点的两个组氨酸和一个赖氨酸的对应物。它属于胰腺 RNase 蛋白超家族，被内皮细胞特异性内吞并转运至细胞核，并在核仁中积累。

The enzyme activity of this recombinant protein is testing in progress, we cannot offer a guarantee yet.

Human

E. coli

Tag Free

P03950 (Q25-P147)

283  [NCBI]

QDNSRYTHFLTQHYDAKPQGRDDRYCESIMRRRGLTSPCKDINTFIHGNKRSIKAICENKNGNPHRENLRISKSSFQVTTCKLHGGSPWPPCQYRATAGFRNVVVACENGLPVHLDQSIFRRP

Approximately 14.0 kDa

Greater than 95% as determined by reducing SDS-PAGE.

无菌粉末.

Lyophilized after extensive dialysis against 20 mM PB, 150 mM NaCl, pH 7.4.

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O. For long term storage it is recommended to add a carrier protein (0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose).

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.

• [1]. Angiogenin.