1. 重组蛋白
  2. Cytokines and Growth Factors CD Antigens Biotinylated Proteins
  3. TNF Superfamily
  4. TNF Superfamily Ligands
  5. APRIL Proteins
  6. APRIL/TNFSF13 Trimer 蛋白, Human (Biotinylated, HEK293, Flag, His-Avi)

APRIL/TNFSF13 Trimer 蛋白, Human (Biotinylated, HEK293, Flag, His-Avi)

目录号: HY-P700661
产品使用指南

APRIL/TNFSF13 是一种 TNF 超家族细胞因子,通过与 TNFRSF13B/TACI 和 TNFRSF17/BCMA 受体结合来影响肿瘤细胞生长。其同源三聚体结构突出了在涉及单核细胞和巨噬细胞的致癌过程和免疫功能中的潜在作用。APRIL/TNFSF13 Trimer 蛋白, Human (Biotinylated, HEK293, Flag, His-Avi) 是重组的 APRIL/TNFSF13 蛋白,由 HEK293 表达,带有 N-Flag, C-Avi, N-His 标签。APRIL/TNFSF13 Trimer 蛋白, Human (Biotinylated, HEK293, Flag, His-Avi) 全长 139 个氨基酸,分子量为 55-65 kDa。

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描述

APRIL/TNFSF13 is a TNF superfamily cytokine that affects tumor cell growth by binding to TNFRSF13B/TACI and TNFRSF17/BCMA receptors. Its homotrimeric structure highlights a potential role in oncogenic processes and immune functions involving monocytes and macrophages. APRIL/TNFSF13 Trimer Protein, Human (Biotinylated, HEK293, Flag, His-Avi) is the recombinant human-derived APRIL/TNFSF13 protein, expressed by HEK293 , with N-Flag, C-Avi, N-His labeled tag. The total length of APRIL/TNFSF13 Trimer Protein, Human (Biotinylated, HEK293, Flag, His-Avi) is 139 a.a., with molecular weight of 55-65 kDa.

研究背景

APRIL/TNFSF13 是肿瘤坏死因子 (TNF) 超家族的细胞因子,通过与 TNFRSF13B/TACI 和 TNFRSF17/BCMA 受体结合发挥其生物学作用。作为同源三聚体,APRIL/TNFSF13 参与肿瘤细胞生长的调节,突出了其在致癌过程中的潜在重要性。此外,APRIL/TNFSF13 可能在单核细胞和巨噬细胞介导的免疫过程中发挥作用。通过与特定受体的相互作用,APRIL/TNFSF13 有助于形成控制细胞行为和免疫反应的复杂调节网络。阐明 APRIL/TNFSF13 的多方面功能为其在健康和疾病中的作用提供了宝贵的见解,特别是在肿瘤生物学和免疫系统调节的背景下。

种属

Human

表达系统

HEK293

标签

N-His;N-Avi;N-Flag

蛋白编号

O75888-1 (K112-L250)

基因 ID
蛋白结构
N-term
His-Avi-Flag
APRIL (K112-L250)
Accession # O75888-1
C-term
同用名
CD256; TALL2; TALL-2; TNFSF13; APRIL; APRILFLJ57090; TRDL1; TRDL-1; ZTNF2; 2310026N09Rik
分子量

55-65 kDa

纯度

Greater than 95% as determined by reducing SDS-PAGE.

内毒素含量

<1 EU/μg, determined by LAL method.

文件资料

APRIL/TNFSF13 Trimer Protein, Human (Biotinylated, HEK293, Flag, His-Avi) 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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  • 重组蛋白稀释计算器

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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产品名称:
APRIL/TNFSF13 Trimer Protein, Human (Biotinylated, HEK293, Flag, His-Avi)
目录号:
HY-P700661
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