C1s-A subcomponent 蛋白, Mouse (HEK293, His)

C1s-A subcomponent protein, a serine protease, is pivotal in the classical complement system pathway. Partnering with C1q and C1r, it forms C1, initiating complement activation. Activated by C1r, C1s can subsequently trigger downstream components C2 and C4, influencing the complement system cascade. C1s-A subcomponent Protein, Mouse (HEK293, His) is the recombinant mouse-derived C1s-A subcomponent protein, expressed by HEK293 , with C-His labeled tag. The total length of C1s-A subcomponent Protein, Mouse (HEK293, His) is 673 a.a., with molecular weight of ~76.6 kDa.

C1s-A 亚组分蛋白是一种丝氨酸蛋白酶，在补体系统的经典途径中发挥着至关重要的作用。它与 C1q 和 C1r 结合形成 C1，即该途径的起始成分。被 C1r 激活后，C1s 能够激活下游成分 C2 和 C4，从而促进补体系统中的级联事件。

Biological activity has been tested in vitro.

Mouse

HEK293

C-His

Q8CG14 (E16-D688)

50908  [NCBI]

Approximately 76.6 kDa

Greater than 85% as determined by reducing SDS-PAGE.

溶液.

Supplied as a 0.2 μm filtered solution of PBS, pH 7.4.

<1 EU/μg, determined by LAL method.

N/A.

Stored at -80°C for 1 year. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.

Shipping with dry ice.