1. 重组蛋白
  2. CD Antigens Biotinylated Proteins
  3. B Cell CD Proteins Stem Cell CD Proteins Epithelial cell CD Proteins Cell Adhesion-related CD Proteins
  4. CD24/Heat-stable Antigen
  5. CD24 蛋白, Human (Biotinylated, HEK293, His-Avi)

CD24 蛋白, Human (Biotinylated, HEK293, His-Avi)

目录号: HY-P78913
COA 产品使用指南

CD24 蛋白在各种细胞类型的细胞分化中发挥着关键作用,其信号传导可能由与 CD24 碳水化合物结合的凝集素样配体启动,并由 GPI 锚点释放的第二信使转导。CD24 还调节 B 细胞激活反应,促进 AG 依赖性 B 细胞增殖并防止终末分化为抗体形成细胞。CD24 蛋白, Human (Biotinylated, HEK293, His-Avi) 是重组的 CD24 蛋白,由 HEK293 表达,带有 C-Avi, C-His 标签。

MCE 的所有产品仅用作科学研究或药证申报,我们不为任何个人用途提供产品和服务

SPR 检测服务   重组蛋白定制服务

1.  客户无需承担相应的运输费用。

2.  同一机构(单位)同一产品试用装仅限申领一次,同一机构(单位)一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户

规格 价格 是否有货 数量
Free Sample   Apply now  
5 μg ¥800 In-stock
10 μg ¥1350 In-stock
50 μg ¥3800 In-stock
100 μg   询价  

* Please select Quantity before adding items.

  • 生物活性

  • 技术参数

  • 产品性质

  • 产品资料

描述

The CD24 protein plays a critical role in cellular differentiation in various cell types, and its signaling may be initiated by lectin-like ligands that bind to the CD24 carbohydrate and transduced by second messengers released from GPI anchors. CD24 also regulates B cell activation responses, promoting AG-dependent B cell proliferation and preventing terminal differentiation into antibody-forming cells. CD24 Protein, Human (Biotinylated, HEK293, His-Avi) is the recombinant human-derived CD24 protein, expressed by HEK293 , with C-Avi, C-His labeled tag.

研究背景

CD24 蛋白在各种细胞类型的细胞分化中发挥着关键作用,其信号传导可能由凝集素样配体与 CD24 碳水化合物的结合触发,并通过释放源自 GPI 锚的第二信使进行转导。CD24 还具有调节 B 细胞激活反应、促进 B 细胞 AG 依赖性增殖以及防止其最终分化为抗体形成细胞的功能。与 SIGLEC10 相关,CD24 可能有助于选择性抑制对危险相关分子模式 (DAMP)(例如 HMGB1、HSP70 和 HSP90)的免疫反应,表明其在免疫调节中发挥作用。此外,CD24 还参与自身免疫的控制。它表现出与 LYN 和 FGR 的细胞类型特异性相互作用,在小细胞癌细胞系中与 FRG 结合,在红白血病细胞系 K-562 中以及在伯基特淋巴瘤中与 LYN 结合,突出了其在细胞过程和免疫调节中的多种参与。

生物活性

Immobilized Biotinylated Human CD24 His-Avi at 5 μg/mL (100 μL/well) on Streptavidin precoated (0.5 μg/well) plate can bind Anti-CD24 MAb (SN3) with a linear range of 0.6-10 ng/mL.

种属

Human

表达系统

HEK293

标签

C-Avi;C-His

蛋白编号

P25063-1 (S27-G59)

基因 ID
同用名
CD24; CD24A
分子量

Approximately 43 kDa

纯度

Greater than 95% as determined by reducing SDS-PAGE.

性状

无菌粉末

组分

Lyophilized a 0.22 μm filtered solution of PBS, 6% Trehalose, pH 7.4.

内毒素含量

<1 EU/μg, determined by LAL method.

复溶方法

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH2O.

保存条件 & 期限

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

运输条件

Room temperature in continental US; may vary elsewhere.

文件资料
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • 复溶计算器

  • 重组蛋白稀释计算器

  • 比活力计算器

The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

您最近查看的产品:

Your information is safe with us. * Required Fields.

   产品名称:

 

* 需求量:

* 客户姓名:

 

* Email:

* 电话:

 

* 公司或机构名称:

   留言给我们:

Bulk Inquiry

Inquiry Information

产品名称:
CD24 Protein, Human (Biotinylated, HEK293, His-Avi)
目录号:
HY-P78913
需求量: