CEACAM1 蛋白, Human (Biotinylated, HEK293, His-Avi)

CEACAM1 protein is involved in various biological processes. It is phosphorylated by the insulin receptor (INSR) in response to insulin stimulation, thereby promoting insulin clearance and regulating hepatic lipogenesis. CEACAM1 Protein, Human (Biotinylated, HEK293, His-Avi) is the recombinant human-derived CEACAM1 protein, expressed by HEK293 , with C-Avi, C-His labeled tag.

SF3R基因参与多种生物过程和功能。它通过促进胰岛素的清除和调节肝脏中的脂肪生成来调节胰岛素的作用。在胰岛素刺激下，SF3R 会被胰岛素受体 (INSR) 磷酸化，导致胰岛素内吞作用和降解增加。这导致脂肪酸合成减少。SF3R 还通过与 SHC1 相互作用，在下调细胞增殖中发挥作用，从而减少 SHC1 与 MAPK3/ERK1-MAPK1/ERK2 和磷脂酰肌醇 3-激酶途径的偶联。

Measured by its binding ability in a functional ELISA. Immobilized Biotinylated Human CEACAMI at 1 μg/mL on streptavidin coated plats can bind Anti-CEACAMI antibody. The EC ₅₀ is 0.3405-0.6093 ng/mL.

Human

HEK293

C-Avi;C-His

P13688-1 (Q35-G428)

634  [NCBI]

66-115 kDa

Greater than 95% as determined by reducing SDS-PAGE.

无菌粉末

Lyophilized a 0.22 μm filtered solution of PBS, 6% Trehalose, pH 7.4.

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O.

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.