COPZ1 蛋白, Human/Mouse/Rat (His)

The COPZ1 protein is a key coating subunit essential for intracellular protein transport.In coat isoform complexes, it binds to a dilysine motif that facilitates reversible association with Golgi vesicles.COPZ1 Protein, Human/Mouse/Rat (His) is the recombinant COPZ1 protein, expressed by E.coli , with N-His labeled tag.

COPZ1 蛋白是外壳蛋白的重要组成部分，外壳蛋白是一种胞质蛋白复合物，在细胞内蛋白转运中发挥着关键作用。该复合物与二赖氨酸基序结合，并与高尔基体非网格蛋白包被的囊泡形成可逆缔合，促进生物合成蛋白从内质网 (ER) 通过高尔基体转运至反式高尔基体网络。外壳复合体对于高尔基体膜囊泡的出芽是必不可少的，并且在二赖氨酸标记蛋白从高尔基体到内质网的逆行转运中发挥着至关重要的作用。外壳体的 zeta 亚基参与调节外壳组装，从而由于其在外壳体复合物内的缔合-解离特性而影响生物合成蛋白质的转运速率。该寡聚复合物至少包含α、β、β'、γ、δ、ε和zeta亚基。

Rat; Mouse

E. coli

N-His

P61923/NP_001101587.1 (M1-R177)

22818  [NCBI]

MEALILEPSLYTVKAILILDNDGDRLFAKYYDDTYPSVKEQKAFEKNIFNKTHRTDSEIALLEGLTVVYKSSIDLYFYVIGSSYENELMLMAVLNCLFDSLSQMLRKNVEKRALLENMEGLFLAVDEIVDGGVILESDPQQVVHRVALRGEDVPLTEQTVSQVLQSAKEQIKWSLLR

Approximately 22.4 kDa.

• 
  Greater than 95% as determined by reducing SDS-PAGE.

无菌粉末

Lyophilized from a 0.2 μm filtered solution of 50 mM Tris, 50 mM Arg, pH 8.5. or 50 mM Tris-HCL, 300 mM NaCl, pH 7.4.

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O. For long term storage it is recommended to add a carrier protein (0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose).

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.