1. 重组蛋白
  2. Cytokines and Growth Factors
  3. TNF Superfamily
  4. TNF Receptor Superfamily
  5. EDA2R
  6. EDA2R/XEDAR 蛋白, Mouse (HEK293, His)

EDA2R/XEDAR 蛋白, Mouse (HEK293, His)

目录号: HY-P72663
产品使用指南

EDA2R/XEDAR 蛋白是 EDA 同工型 A2(但不是 A1)的受体,在激活 NF-kappa-B 和 JNK 通路中发挥关键作用。如蛋白质相似性所示,这种激活涉及与 TRAF3 和 TRAF6 的结合。EDA2R/XEDAR 蛋白, Mouse (HEK293, His) 是重组的 EDA2R/XEDAR 蛋白,由 HEK293 表达,带有 C-6*His 标签。EDA2R/XEDAR 蛋白, Mouse (HEK293, His) 全长 138 个氨基酸,分子量约为 ~26 kDa。

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10 μg ¥600 询问价格 & 货期
50 μg ¥1700 询问价格 & 货期

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描述

The EDA2R/XEDAR protein is a receptor for EDA isoform A2 (but not A1) and plays a key role in activating the NF-kappa-B and JNK pathways. This activation involves binding to TRAF3 and TRAF6, as indicated by protein similarity. EDA2R/XEDAR Protein, Mouse (HEK293, His) is the recombinant mouse-derived EDA2R/XEDAR protein, expressed by HEK293 , with C-6*His labeled tag. The total length of EDA2R/XEDAR Protein, Mouse (HEK293, His) is 138 a.a., with molecular weight of ~26 kDa.

研究背景

EDA2R/XEDAR 蛋白被鉴定为 EDA 同工型 A2(但不是 A1)的受体,在介导 NF-kappa-B 和 JNK 通路的激活中发挥着关键作用。正如与相关蛋白的相似性所表明的,激活过程似乎涉及 EDA2R/XEDAR 与 TRAF3 和 TRAF6 的结合。此外,EDA2R/XEDAR 与 TRAF1、TRAF3 和 TRAF6 相关,进一步表明其参与与免疫和炎症反应相关的信号通路。复杂的相互作用和激活机制强调了 EDA2R/XEDAR 在细胞信号级联中的重要性,对各种生理过程和细胞反应具有潜在影响。

种属

Mouse

表达系统

HEK293

标签

C-6*His

蛋白编号

Q8BX35 (M1-T138)

基因 ID
蛋白结构
N-term
EDA2R (M1-T138)
Accession # Q8BX35
6*His
C-term
同用名
Tumor necrosis factor receptor superfamily member 27; EDA-A2 receptor; EDA2R; TNFRSF27; XEDAR
氨基酸序列

MDCQENEYRDQWGRCVTCQQCGPGQELSKDCGYGEGGDAHCIVCPPRKYKSTWGHHRCQTCITCAVINRVQKANCTNTSNAICGDCLPRFYRKTRIGGLQDQECIPCTKQTPSSEVQCTFQLSLVKVDAHTVPPREAT

分子量

Approximately 26-28 kDa

纯度

Greater than 95% as determined by reducing SDS-PAGE.

内毒素含量

<1 EU/μg, determined by LAL method.

文件资料

EDA2R/XEDAR Protein, Mouse (HEK293, His) 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • 复溶计算器

  • 重组蛋白稀释计算器

  • 比活力计算器

The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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产品名称:
EDA2R/XEDAR Protein, Mouse (HEK293, His)
目录号:
HY-P72663
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