EGF 蛋白, Rat (CHO)

EGF Protein, Rat (CHO) is a potent epidermal growth factor, promotes epithelial proliferation and migration, and increases epithelial wound closure and shortens healing time.

表皮生长因子由上皮细胞分泌，促进多种组织中的上皮增殖和迁移，促进上皮伤口闭合，缩短愈合时间^[1]。表皮生长因子在皮肤发育和体内平衡中发挥着关键作用，在表皮屏障中显示出保护功能。表皮生长因子还在发炎的皮肤组织中显示出免疫调节活性^[2]。

The ED₅₀ is <0.1 ng/mL as measured by 3T3 cells.

Rat

CHO

Tag Free

P07522 (N974-R1026)

25313  [NCBI]

MNSNTGCPPSYDGYCLNGGVCMYVESVDRYVCNCVIGYIGERCQHRDLRWWKLR

Approximately 6 kDa

Greater than 95% as determined by reducing SDS-PAGE.

无菌粉末.

Lyophilized after extensive dialysis against PBS.

<0.2 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O. For long term storage it is recommended to add a carrier protein (0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose).

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.

• [1]. Palencia L, et al. Epidermal growth factor mediated healing in stem cell-derived vocal fold mucosa. J Surg Res. 2015 Jul;197(1):32-8.  [Content Brief]

  [2]. Choi SY, et al. Epidermal Growth Factor Relieves Inflammatory Signals in Staphylococcus aureus-Treated Human Epidermal Keratinocytes and Atopic Dermatitis-Like Skin Lesions in Nc/Nga Mice. Biomed Res Int. 2018 May 15;2018:9439182.  [Content Brief]