1. 重组蛋白
  2. CAR-T related Proteins CD Antigens
  3. Epithelial Cell Adhesion Molecule (EpCAM) Stem Cell CD Proteins Dendritic Cell CD Proteins Epithelial cell CD Proteins
  4. CD326/EpCAM
  5. EpCAM/TROP1 蛋白, Rat (HEK293, Fc)

EpCAM/TROP1 蛋白, Rat (HEK293, Fc)

目录号: HY-P74173
产品使用指南 技术支持

EpCAM/TROP1 蛋白作为一种多功能分子,促进粘膜上皮中肠上皮细胞 (IEC) 和上皮内淋巴细胞 (IEL) 之间的均匀相互作用。这表明在建立抵抗粘膜感染的免疫屏障方面发挥着至关重要的作用。EpCAM/TROP1 蛋白, Rat (HEK293, Fc) 是重组的 EpCAM/TROP1 蛋白,由 HEK293 表达,带有 C-hFc 标签。

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描述

The EpCAM/TROP1 protein serves as a multifunctional molecule that promotes homogeneous interactions between intestinal epithelial cells (IECs) and intraepithelial lymphocytes (IELs) in the mucosal epithelium. This suggests a crucial role in establishing an immune barrier against mucosal infection. EpCAM/TROP1 Protein, Rat (HEK293, Fc) is the recombinant rat-derived EpCAM/TROP1 protein, expressed by HEK293 , with C-hFc labeled tag.

研究背景

EpCAM/TROP1 蛋白具有多方面的作用,可能充当物理同源相互作用分子,促进粘膜上皮的肠上皮细胞 (IEC) 和上皮内淋巴细胞 (IEL) 之间的直接接触。这种相互作用表明在建立免疫屏障方面具有关键功能,作为抵御粘膜感染的第一道防线。除了参与粘膜免疫之外,EpCAM/TROP1 在胚胎干细胞的增殖和分化中也发挥着重要作用。此外,它通过上调 FABP5、MYC 以及细胞周期蛋白 A 和 E 的表达来发挥调节作用,表明 EpCAM/TROP1 参与关键细胞过程的调节。它的单体性质以及与磷酸化 CLDN7 的相互作用强调了其分子相互作用的复杂性,揭示了其在细胞生理学中的多种功能。

种属

Rat

表达系统

HEK293

标签

C-hFc

蛋白编号

O55159 (Q24-T266)

基因 ID
蛋白结构
N-term
EpCAM (Q24-T266)
Accession # O55159
hFc
C-term
同用名
Epithelial cell adhesion molecule; Ep-CAM; EGP; KSA; CD326; TROP1
分子量

Approximately 61&37 kDa

纯度

Greater than 95% as determined by reducing SDS-PAGE.

内毒素含量

<1 EU/μg, determined by LAL method.

文件资料
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • 复溶计算器

  • 重组蛋白稀释计算器

  • 比活力计算器

The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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产品名称:
EpCAM/TROP1 Protein, Rat (HEK293, Fc)
目录号:
HY-P74173
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