EphA1 蛋白, Human (HEK293, hFc)

EphA1 Protein, a receptor tyrosine kinase, engages in bidirectional signaling with membrane-bound ephrin-A ligands. Activation by EFNA1 regulates cell attachment, motility, angiogenesis, and proliferation. EphA1 may also play a role in apoptosis. EphA1 Protein, Human (HEK293, hFc) is the recombinant human-derived EphA1 protein, expressed by HEK293 , with C-hFc labeled tag.

EphA1 蛋白是一种受体酪氨酸激酶，与邻近细胞上膜结合的肝配蛋白 A 配体相互作用，产生接触依赖性双向信号传导。该受体介导正向信号传导和反向信号传导途径。其高亲和力配体 EFNA1 的激活可调节各种细胞过程，包括细胞附着、运动、血管生成和增殖。此外，EphA1 可能在细胞凋亡中发挥作用。

Immobilized human EFNA1-His at 10 μg/ml (100 μL /well) can bind human EPHA1-Fc, The EC₅₀ of human EPHA1-Fc is 9.6-30 ng/mL.

Human

HEK293

C-hFc

EAL23789.1 (K26-E547)

2041  [NCBI]

Approximately 83.3 kDa

Greater than 90% as determined by reducing SDS-PAGE.

溶液

Supplied as a 0.2 μm filtered solution of PBS, pH 7.4.

<1 EU/μg, determined by LAL method.

N/A.

Stored at -80°C for 1 year. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.

Shipping with dry ice.