2. 重组蛋白
  3. Cytokines and Growth Factors Receptor Proteins Enzymes & Regulators
  4. Ephrin/Eph Family Receptor Tyrosine Kinases Protein Tyrosine Kinases
  5. Eph Receptors
  6. EphA6
  7. EphA6 蛋白, Mouse (HEK293, Fc)

EphA6 蛋白, Mouse (HEK293, Fc)

目录号: HY-P75744
产品使用指南

EphA6 蛋白是一种受体酪氨酸激酶，与 GPI 锚定的肝配蛋白 A 配体混杂结合，促进接触依赖性双向信号传导。EphA6 介导细胞间复杂的信号交换，通过正向和反向信号通路在多种细胞过程中发挥着至关重要的作用。EphA6 蛋白, Mouse (HEK293, Fc) 是重组的 EphA6 蛋白，由 HEK293 表达，带有 C-hFc 标签。

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描述

EphA6 Protein, a receptor tyrosine kinase, engages in promiscuous binding with GPI-anchored ephrin-A ligands, facilitating contact-dependent bidirectional signaling. EphA6 mediates intricate signaling exchanges between cells, playing a crucial role in diverse cellular processes through both forward and reverse signaling pathways. EphA6 Protein, Mouse (HEK293, Fc) is the recombinant mouse-derived EphA6 protein, expressed by HEK293 , with C-hFc labeled tag.
研究背景

EphA6 蛋白是一种受体酪氨酸激酶，与相邻细胞上 GPI 锚定的肝配蛋白 A 家族配体表现出混杂结合，启动接触依赖性双向信号传导至相邻细胞。源自受体的下游途径被称为正向信号传导，而肝配蛋白配体下游的途径被称为反向信号传导，这与其他 Eph 受体的相似性表明了这一点。这种相互作用凸显了 EphA6 在介导细胞间复杂信号交换中的作用，通过双向通信促进不同的细胞过程。
种属

Mouse
表达系统

HEK293
标签

C-hFc
蛋白编号

AAB53836.1 (S28-Q546)
基因 ID

/
蛋白结构
N-term
EphA6 (S28-Q546)
Accession # AAB53836.1
hFc
C-term
同用名
Ephrin type-A receptor 6; EPH homology kinase 2; EHK-2; Epha6
分子量

Approximately 110 kDa
纯度

Greater than 90% as determined by reducing SDS-PAGE
内毒素含量

<1 EU/μg, determined by LAL method.
文件资料
产品使用指南 (1213 KB)

EphA6 Protein, Mouse (HEK293, Fc) 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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