1. 重组蛋白
  2. Enzymes & Regulators
  3. Isomerases (EC 5)
  4. HPGDS 蛋白, Human

HPGDS蛋白是一种具有双功能的多功能酶,其C端和N端结构域具有不同的活性。C 末端充当环氧化物水解酶,通过降解有害环氧化物和调节生理介质水平来促进外源代谢。HPGDS 蛋白, Human 是重组的 HPGDS 蛋白,由 E. coli 表达,不带标签。

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规格 价格 是否有货
10 μg ¥1800 询问价格 & 货期
50 μg ¥5000 询问价格 & 货期

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  • 生物活性

  • 技术参数

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  • 产品资料

描述

HPGDS protein is a multifunctional enzyme with bifunctionality, and its C-terminal and N-terminal domains have different activities.The C terminus acts as an epoxide hydrolase, promoting xenobiotic metabolism by degrading harmful epoxides and regulating physiological mediator levels.HPGDS Protein, Human is the recombinant human-derived HPGDS protein, expressed by E.coli , with tag free.

研究背景

EPHX2 是一种多功能酶,具有双功能性,其 C 端和 N 端结构域具有不同的活性。C 末端结构域充当环氧化物水解酶,靶向氧化烯烃和氧化芳烃,通过降解潜在有害的环氧化物来促进外源代谢。此外,它还在调节生理介质的稳态水平方面发挥作用。另一方面,N 末端结构域表现出脂质磷酸酶活性,优先选择苏型 9,10-膦酰氧基-羟基-十八烷酸和赤型-9,10-膦酰氧基-羟基-十八烷酸等底物。它还证明了对溶血甘油磷脂的磷酸酶活性,对鞘脂和类异戊二烯磷酸盐的溶血脂具有不同的活性。EPHX2 的多功能功能有助于其参与多种生物过程,反映了其在细胞稳态中的重要性。

种属

Human

表达系统

E. coli

标签

Tag Free

蛋白编号

O60760 (M1-L199)

基因 ID
蛋白结构
N-term
HPGDS (M1-L199)
Accession # O60760
C-term
同用名
Glutathione-Dependent PGD Synthase; Glutathione-Requiring Prostaglandin D Synthase; Prostaglandin-H2 D-Isomerase; HPGDS; GSTS; PGDS; PTGDS2
氨基酸序列

MPNYKLTYFNMRGRAEIIRYIFAYLDIQYEDHRIEQADWPEIKSTLPFGKIPILEVDGLTLHQSLAIARYLTKNTDLAGNTEMEQCHVDAIVDTLDDFMSCFPWAEKKQDVKEQMFNELLTYNAPHLMQDLDTYLGGREWLIGNSVTWADFYWEICSTTLLVFKPDLLDNHPRLVTLRKKVQAIPAVANWIKRRPQTKL

分子量

Approximately 26.0 kDa

纯度

Greater than 95% as determined by reducing SDS-PAGE.

内毒素含量

<1 EU/μg, determined by LAL method.

文件资料

HPGDS Protein, Human 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • 复溶计算器

  • 重组蛋白稀释计算器

  • 比活力计算器

The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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产品名称:
HPGDS Protein, Human
目录号:
HY-P71036
需求量: