1. 重组蛋白
  2. Enzymes & Regulators
  3. Oxidoreductases (EC 1)
  4. L-xylulose reductase/DCXR 蛋白, Human (His)

L-xylulose reductase/DCXR 蛋白, Human (His)

目录号: HY-P70082
COA 产品使用指南

L-木酮糖还原酶由DCXR基因编码,通过催化NADPH依赖性的各种戊糖、丁糖、三糖、α-二羰基化合物和L-木酮糖的还原作用,在细胞代谢中发挥着至关重要的作用。这种酶积极参与葡萄糖代谢的糖醛酸循环。L-xylulose reductase/DCXR 蛋白, Human (His) 是重组的 L-木酮糖还原酶/DCXR 蛋白,由 E. coli 表达,带有 N-6*His 标签。L-xylulose reductase/DCXR 蛋白, Human (His) 全长 244 个氨基酸,分子量约为 ~28.0 kDa。

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规格 价格 是否有货 数量
5 μg ¥470 In-stock
10 μg ¥800 In-stock
50 μg ¥2250 In-stock
100 μg ¥3800 In-stock
> 100 μg   询价  

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描述

L-xylulose reductase, encoded by the DCXR gene, plays a vital role in cellular metabolism by catalyzing the NADPH-dependent reduction of various pentoses, tetoses, trisaccharides, α-dicarbonyl compounds, and L-xylulose role. This enzyme is actively involved in the uronic acid cycle of glucose metabolism. L-xylulose reductase/DCXR Protein, Human (His) is the recombinant human-derived L-xylulose reductase/DCXR protein, expressed by E. coli , with N-6*His labeled tag. The total length of L-xylulose reductase/DCXR Protein, Human (His) is 244 a.a., with molecular weight of ~28.0 kDa.

研究背景

L-木酮糖还原酶由 DCXR 基因编码,是一种多功能酶,可催化各种戊糖、丁糖、丙糖、α-二羰基化合物,特别是 L-木酮糖的 NADPH 依赖性还原。作为葡萄糖代谢中糖醛酸循环的一部分,这种酶参与多种生化反应,有助于不同糖的细胞加工。值得注意的是,L-木酮糖还原酶与近端肾小管的吸水和细胞渗透压调节有关。通过产生木糖醇(一种渗透剂),这种酶有助于防止肾小管内的渗透压,显示出其在维持肾脏细胞稳态方面的潜在作用。L-木酮糖还原酶的多功能性强调了其在糖代谢和细胞渗透压调节中的重要性,为了解其更广泛的生理影响提供了见解。

生物活性

The enzyme activity of this recombinant protein is testing in progress, we cannot offer a guarantee yet.

种属

Human

表达系统

E. coli

标签

N-6*His

蛋白编号

Q7Z4W1 (M1-C244)

基因 ID
蛋白结构
N-term
6*His
DCXR (M1-C244)
Accession # Q7Z4W1
C-term
同用名
rHuL-xylulose reductase/DCXR, His; L-Xylulose Reductase; XR; Carbonyl Reductase II; Dicarbonyl/L-Xylulose Reductase; Kidney Dicarbonyl Reductase; kiDCR; Sperm Surface Protein P34H; DCXR
氨基酸序列

MELFLAGRRVLVTGAGKGIGRGTVQALHATGARVVAVSRTQADLDSLVRECPGIEPVCVDLGDWEATERALGSVGPVDLLVNNAAVALLQPFLEVTKEAFDRSFEVNLRAVIQVSQIVARGLIARGVPGAIVNVSSQCSQRAVTNHSVYCSTKGALDMLTKVMALELGPHKIRVNAVNPTVVMTSMGQATWSDPHKAKTMLNRIPLGKFAEVEHVVNAILFLLSDRSGMTTGSTLPVEGGFWAC

分子量

Approximately 28.0 kDa

纯度

Greater than 90% as determined by reducing SDS-PAGE

性状

溶液.

组分

Supplied as a 0.2 μm filtered solution of 50 mM Tris, 300 mM NaCl, 30% Glycerol, pH 7.4.

内毒素含量

<1 EU/μg, determined by LAL method.

保存条件 & 期限

Stored at -80°C for 1 year. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.

运输条件

Shipping with dry ice.

文件资料

L-xylulose reductase/DCXR Protein, Human (His) 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • 复溶计算器

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  • 比活力计算器

The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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产品名称:
L-xylulose reductase/DCXR Protein, Human (His)
目录号:
HY-P70082
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