1. 重组蛋白
  2. CD Antigens Receptor Proteins
  3. NK Cell CD Proteins Leukocyte Immunoglobin-like Receptors
  4. LIR-9/CD85f LIR-9/CD85f
  5. LILRA5/CD85f 蛋白, Human (HEK293, His)

LILRA5/CD85f 蛋白, Human (HEK293, His)

目录号: HY-P72521
产品使用指南

LILRA5/CD85f 蛋白可能独立于 MHC I 类抗原的识别而触发先天免疫反应。这一独特的功能表明其在早期防御病原体方面发挥着独特的作用,通过独立于 MHC I 类抗原识别的途径发挥作用。LILRA5/CD85f 蛋白, Human (HEK293, His) 是重组的 LILRA5/CD85f 蛋白,由 HEK293 表达,带有 C-6*His 标签。

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描述

The LILRA5/CD85f protein may trigger innate immune responses independently of recognition of MHC class I antigens. This unique feature suggests a unique role in early defense against pathogens, acting through a pathway that is independent of MHC class I antigen recognition. LILRA5/CD85f Protein, Human (HEK293, His) is the recombinant human-derived LILRA5/CD85f protein, expressed by HEK293 , with C-6*His labeled tag.

研究背景

LILRA5/CD85f 蛋白被认为可能在触发先天免疫反应中发挥作用,表明其参与针对病原体的早期防御机制。然而,它似乎在识别任何 I 类主要组织相容性复合体 (MHC) 抗原方面没有作用。这一独特的特征表明,LILRA5/CD85f 可能通过独立于 I 类 MHC 抗原识别的途径发挥其免疫调节作用,突出了其在先天免疫反应的复杂景观中的独特作用。其参与触发先天免疫的具体分子机制仍有待充分阐明,需要进一步探索其在免疫系统中的功能意义。

种属

Human

表达系统

HEK293

标签

C-6*His

蛋白编号

A6NI73-1 (G42-R268)

基因 ID
蛋白结构
N-term
LILRA5 (G42-R268)
Accession # A6NI73-1
6*His
C-term
同用名
Leukocyte immunoglobulin-like receptor subfamily A member 5; LILRA5; ILT-11; LIR-9; CD85f; LILRB7
氨基酸序列

GNLSKATLWAEPGSVISRGNSVTIRCQGTLEAQEYRLVKEGSPEPWDTQNPLEPKNKARFSIPSMTEHHAGRYRCYYYSPAGWSEPSDPLELVVTGFYNKPTLSALPSPVVTSGENVTLQCGSRLRFDRFILTEEGDHKLSWTLDSQLTPSGQFQALFPVGPVTPSHRWMLRCYGSRRHILQVWSEPSDLLEIPVSGAADNLSPSQNKSDSGTASHLQDYAVENLIR

分子量

35-40 kDa

纯度

Greater than 95% as determined by reducing SDS-PAGE.

内毒素含量

<1 EU/μg, determined by LAL method.

文件资料
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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  • 重组蛋白稀释计算器

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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产品名称:
LILRA5/CD85f Protein, Human (HEK293, His)
目录号:
HY-P72521
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