2. 重组蛋白
  3. CAR-T related Proteins Receptor Proteins Biotinylated Proteins
  4. Cell Adhesion Molecules (CAMs)
  5. Immunoglobulin-like Cell Adhesion Molecules
  6. Nectin-4
  7. Nectin-4 蛋白, Human (HEK293, His-Avi)

Nectin-4 蛋白, Human (HEK293, His-Avi)

目录号: HY-P78374
产品使用指南

Nectin-4 蛋白 IgV 结构域在细胞粘附中至关重要，参与反同性和反异性相互作用，尤其是与 NECTIN1 的相互作用。虽然它不充当α-疱疹病毒进入受体，但它充当麻疹病毒的受体，使病毒能够进入宿主细胞。这种双重作用强调了 Nectin-4 在细胞粘附中的重要性及其作为麻疹病毒感染受体的特殊作用。Nectin-4 蛋白, Human (HEK293, His-Avi) 是重组的 Nectin-4 蛋白，由 HEK293 表达，带有 C-Avi, C-His 标签。

MCE 的所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务

SPR 检测服务   重组蛋白定制服务

1.  客户无需承担相应的运输费用。

2.  同一机构（单位）同一产品试用装仅限申领一次，同一机构（单位）一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户。

规格 是否有货
50 μg   询价  
100 μg   询价  

* Please select Quantity before adding items.

Top Publications Citing Use of Products

  • 生物活性

  • 技术参数

  • 产品性质

  • 产品资料

描述

The Nectin-4 Protein IgV domain is pivotal in cell adhesion, participating in trans-homophilic and -heterophilic interactions, notably with NECTIN1. While it doesn't serve as an alpha-herpesvirus entry receptor, it functions as a receptor for measles virus, enabling virus entry into host cells. This dual role underscores the importance of Nectin-4 in cell adhesion and its specific role as a measles virus infection receptor. Nectin-4 Protein, Human (HEK293, His-Avi) is the recombinant human-derived Nectin-4 protein, expressed by HEK293 , with C-Avi, C-His labeled tag.
研究背景

Nectin-4 蛋白 IgV 结构域在细胞粘附中发挥着至关重要的作用，参与反同性和反异性相互作用。具体来说，它与 NECTIN1 形成相互作用，有助于细胞粘附过程。然而，它不能作为α-疱疹病毒进入细胞的受体。在微生物感染的情况下，Nectin-4 IgV 结构域充当麻疹病毒的受体，促进病毒进入宿主细胞。这凸显了 Nectin-4 在细胞粘附中的双重作用及其作为麻疹病毒感染特异性受体的重要性。
种属

Human
表达系统

HEK293
标签

C-Avi;C-His
蛋白编号

Q96NY8-1 (G32-V351)
基因 ID
蛋白结构
N-term
Nectin-4 (G32-V351)
Accession # Q96NY8-1
His-Avi
C-term
同用名
EDSS1; LNIR; Nectin4; PRR4; NECTIN4; PVRL4
分子量

46-48 kDa
纯度

Greater than 95% as determined by Tris-Bis PAGE.
内毒素含量

<1 EU/μg, determined by LAL method.
文件资料
产品使用指南 (1213 KB)

Nectin-4 Protein, Human (HEK293, His-Avi) 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • 复溶计算器

  • 重组蛋白稀释计算器

  • 比活力计算器

The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

您最近查看的产品:

Your information is safe with us. * Required Fields.

   产品名称：

  

* 需求量：

* 客户姓名：

 

* Email：

* 电话：

 

* 公司或机构名称：

   留言给我们：

Bulk Inquiry

Inquiry Information

产品名称：
Nectin-4 Protein, Human (HEK293, His-Avi)
目录号：
HY-P78374
需求量：

Request for HNMR Report

Please fill out this form to request the QC report. We will send it to your Email address shortly.

Your information is safe with us. * Required Fields.

   产品名称：

  

* Lot #：

* 客户姓名：

 

* Email：

* 电话：

 

* 公司或机构名称：

   留言给我们：

Request for HNMR Report

We have received your request and will respond to you as soon as possible.

嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z