2. 重组蛋白
  3. Viral Proteins
  4. Influenza Viruses Proteins
  5. Influenza Virus Neuraminidase
  6. Neuraminidase 蛋白, M.viridifaciens (His)

Neuraminidase 蛋白, M.viridifaciens (His)

目录号: HY-P77073
产品使用指南

神经氨酸酶是唾液酸酶的一种亚型，与微生物感染的致病潜力相关。作为一种酶，神经氨酸酶在催化从糖蛋白和糖脂中去除末端唾液酸残基方面发挥着至关重要的作用。Neuraminidase 蛋白, M.viridifaciens (His) 是重组的 神经氨酸酶蛋白，由 E. coli 表达，带有 N-His 标签。Neuraminidase 蛋白, M.viridifaciens (His) 全长 362 个氨基酸，分子量约为 ~39.7 kDa。

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描述

Neuraminidase is a subtype of sialidase associated with the pathogenic potential of microbial infections. As an enzyme, neuraminidase plays a crucial role in catalyzing the removal of terminal sialic acid residues from glycoproteins and glycolipids. Neuraminidase Protein, M.viridifaciens (His) is the recombinant Neuraminidase protein, expressed by E. coli , with N-His labeled tag. The total length of Neuraminidase Protein, M.viridifaciens (His) is 362 a.a., with molecular weight of ~39.7 kDa.
研究背景

神经氨酸酶是唾液酸酶的一种亚型，与微生物感染的潜在致病性有关。作为一种酶，神经氨酸酶在催化从糖蛋白和糖脂中去除末端唾液酸残基方面发挥着至关重要的作用。这种活性使病毒或细菌能够通过促进新形成的病毒颗粒的释放或通过增强其粘附和侵入宿主细胞的能力来促进其在宿主内的传播。神经氨酸酶被认为是多种病原体的关键毒力因子，抗病毒药物以抑制其酶活性并阻碍感染的进展为目标。了解神经氨酸酶的功能和机制对于制定有效的微生物感染策略至关重要。
种属

Others
表达系统

E. coli
标签

N-His
蛋白编号

BAA00852 (P42-G403)
基因 ID

/
蛋白结构
N-term
His
Neuraminidase (P42-G403)
Accession # BAA00852
C-term
同用名
Sialidase; Neuraminidase; nedA
分子量

Approximately 39.7 kDa
纯度

Greater than 95% as determined by reducing SDS-PAGE
内毒素含量

<1 EU/μg, determined by LAL method.
文件资料
产品使用指南 (1213 KB)

Neuraminidase Protein, M.viridifaciens (His) 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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