1. 重组蛋白
  2. Receptor Proteins
  3. OSCAR 蛋白, Human (HEK293, Fc)

OSCAR 蛋白, Human (HEK293, Fc)

目录号: HY-P78011
产品使用指南

OSCAR 蛋白是骨生物学的关键协调者,对破骨细胞生成起着至关重要的调节作用,影响破骨细胞的分化、形成和成熟。OSCAR 专注于骨骼,在维持骨骼稳态和结构完整性方面发挥着关键作用,有助于骨重塑的动态平衡。OSCAR 蛋白, Human (HEK293, Fc) 是重组的 OSCAR 蛋白,由 HEK293 表达,带有 C-hFc 标签。

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描述

OSCAR Protein, a key orchestrator in bone biology, crucially regulates osteoclastogenesis, influencing osteoclast differentiation, formation, and maturation. Focused on bones, OSCAR plays a pivotal role in maintaining skeletal homeostasis and structural integrity, contributing to the dynamic equilibrium of bone remodeling. OSCAR Protein, Human (HEK293, Fc) is the recombinant human-derived OSCAR protein, expressed by HEK293 , with C-hFc labeled tag.

研究背景

OSCAR 是骨生物学的关键协调者,是破骨细胞生成的关键调节者,在破骨细胞分化的复杂过程中发挥着重要影响。OSCAR 以骨骼特异性为重点,发挥其监管能力来微调破骨细胞形成和成熟的机制。通过其在破骨细胞生成中的关键作用,OSCAR 有助于骨重塑的动态平衡,在维持骨骼稳态和结构完整性方面发挥着至关重要的作用。

种属

Human

表达系统

HEK293

标签

C-hFc

蛋白编号

Q8IYS5-2 (D19-N229)

基因 ID
蛋白结构
N-term
OSCAR (D19-N229)
Accession # Q8IYS5-2
hFc
C-term
同用名
mOSCAR; OSCAR; PIGR3; PIgR-3; Poly-Ig receptor 3; MGC33613
分子量

60-70 kDa

纯度

Greater than 95% as determined by Tris-Bis PAGE.

内毒素含量

<1 EU/μg, determined by LAL method.

文件资料

OSCAR Protein, Human (HEK293, Fc) 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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产品名称:
OSCAR Protein, Human (HEK293, Fc)
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HY-P78011
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