PAEP 蛋白, Human (HEK293, Myc, His)

PAEP protein is a glycoprotein that regulates fertilization steps and exhibits immunomodulatory effects. PAEP Protein, Human (HEK293, Myc, His) is the recombinant human-derived PAEP protein, expressed by HEK293 , with C-Myc, N-10*His labeled tag.

PAEP 蛋白是一种糖蛋白，复杂地调节受精过程中的关键步骤，同时还发挥免疫调节作用。在生殖组织中，已鉴定出四种不同的糖型，即糖蛋白-S、-A、-F 和 -C，每种糖型都具有独特的糖基化模式和生物活性。例如，Glycodelin-A 具有避孕和免疫抑制活性。另一方面，Glycodelin-C 在刺激精子与透明带的结合方面发挥作用。相反，Glycodelin-F 可抑制精子与透明带的结合，并显着抑制孕酮诱导的精子顶体反应。此外，精浆中存在的 Glycodelin-S 可以维持人类精子的无能力状态。该蛋白质形成同二聚体，进一步强调其在协调受精过程中的关键事件和调节免疫反应方面的结构复杂性和功能多样性。

Human

HEK293

C-Myc;N-10*His

P09466-1 (M19-F180)

5047  [NCBI]

MDIPQTKQDLELPKLAGTWHSMAMATNNISLMATLKAPLRVHITSLLPTPEDNLEIVLHRWENNSCVEKKVLGEKTENPKKFKINYTVANEATLLDTDYDNFLFLCLQDTTTPIQSMMCQYLARVLVEDDEIMQGFIRAFRPLPRHLWYLLDLKQMEEPCRF

Approximately 30 kDa

Greater than 90% as determined by reducing SDS-PAGE.

无菌粉末.

Lyophilized a 0.2 μm filtered solution of PBS, 6% Trehalose, pH 7.4.

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O.

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.