2. 重组蛋白
  3. Immune Checkpoint Proteins CD Antigens Biotinylated Proteins
  4. Inhibitory Checkpoint Molecules T Cell CD Proteins Macrophage CD Proteins
  5. PD-1
  6. PD-1 蛋白, Mouse (Biotinylated, HEK293, Fc)

PD-1 蛋白, Mouse (Biotinylated, HEK293, Fc)

目录号: HY-P700808
产品使用指南 技术支持

PD-1（程序性细胞死亡 1）蛋白负向调节免疫反应并影响细胞凋亡和耐受诱导等过程。它是一种存在于质膜外部并在视网膜中表达的跨膜蛋白。PD-1 蛋白, Mouse (Biotinylated, HEK293, Fc) 是重组的 PD-1 蛋白，由 HEK293 表达，带有 C-hFc 标签。

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SPR 检测服务   重组蛋白定制服务

1.  客户无需承担相应的运输费用。

2.  同一机构（单位）同一产品试用装仅限申领一次，同一机构（单位）一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户。

规格 是否有货
50 μg   询价  
100 μg   询价  

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描述

PD-1 (programmed cell death 1) protein negatively regulates immune responses and affects processes such as apoptosis and tolerance induction. It is a transmembrane protein found on the outside of the plasma membrane and expressed in the retina. PD-1 Protein, Mouse (Biotinylated, HEK293, Fc) is the recombinant mouse-derived PD-1 protein, expressed by HEK293 , with C-hFc labeled tag.
研究背景

PD-1（程序性细胞死亡1）蛋白在免疫反应的负向调节中发挥着至关重要的作用，作用于细胞凋亡过程的负向调节、耐受诱导的负向调节和细胞凋亡过程的正向调节等过程的上游。这种跨膜蛋白位于质膜的外侧，并在视网膜中表达。PD-1与多种疾病相关，包括自身免疫性疾病、乙型和丙型肝炎、肝细胞癌和狼疮性肾炎。PD-1 在成人胸腺和卵巢中的偏向表达表明其参与这些组织内的免疫调节。
种属

Mouse
表达系统

HEK293
标签

C-hFc
蛋白编号

NP_032824 (L25-Q167)
基因 ID
蛋白结构
N-term
PD-1 (L25-Q167)
Accession # NP_032824
hFc
C-term
同用名
PDCD1; PD1; CD279; SLEB2; PD-1
分子量

60-70 kDa
纯度

Greater than 95% as determined by reducing SDS-PAGE.
内毒素含量

<1 EU/μg, determined by LAL method.
文件资料
产品使用指南 (1213 KB)

PD-1 Protein, Mouse (Biotinylated, HEK293, Fc) 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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  • 重组蛋白稀释计算器

  • 比活力计算器

The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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