2. 重组蛋白
  3. Enzymes & Regulators
  4. Oxidoreductases (EC 1)
  5. PRDX5/Peroxiredoxin-5 蛋白, Human (His)

PRDX5/Peroxiredoxin-5 蛋白, Human (His)

目录号: HY-P73711
产品使用指南

PRDX5 蛋白（或 Peroxiredoxin-5）作为硫醇特异性过氧化物酶发挥着关键作用，可还原过氧化氢和有机氢过氧化物。这种酶活性对于细胞防御氧化应激和解毒过氧化物至关重要。PRDX5/Peroxiredoxin-5 蛋白, Human (His) 是重组的 PRDX5/Peroxiredoxin-5 蛋白，由 E. coli 表达，带有 N-His 标签。

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规格 是否有货
50 μg   询价  
100 μg   询价  

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描述

The PRDX5 protein (or Peroxiredoxin-5) plays a critical role as a thiol-specific peroxidase that reduces hydrogen peroxide and organic hydroperoxides. This enzyme activity is essential for cells to defend against oxidative stress and detoxify peroxides. PRDX5/Peroxiredoxin-5 Protein, Human (His) is the recombinant human-derived PRDX5/Peroxiredoxin-5 protein, expressed by E. coli , with N-His labeled tag.
研究背景

PRDX5，也称为 Peroxiredoxin-5，是一种硫醇特异性过氧化物酶，有助于将过氧化氢和有机氢过氧化物分别还原为水和醇。这种酶活性是细胞防御氧化应激不可或缺的一部分，通过解毒过氧化物发挥保护机制的作用。除了在过氧化物还原中的作用外，PRDX5 还充当过氧化氢介导的信号事件的传感器，强调了它参与与氧化应激反应相关的细胞信号通路。PRDX5 的多方面功能强调了其在维持细胞稳态和协调对氧化挑战的适应性反应方面的重要性。
种属

Human
表达系统

E. coli
标签

N-His
蛋白编号

P30044-1 (M53-L214)
基因 ID
蛋白结构
N-term
His
PRDX5/Peroxiredoxin-5 (M53-L214)
Accession # P30044-1
C-term
同用名
Peroxiredoxin-5; PLP; Prx-V; Prdx5; AOEB166
分子量

Approximately 18.5 kDa
纯度

Greater than 95% as determined by reducing SDS-PAGE.
内毒素含量

<1 EU/μg, determined by LAL method.
文件资料
产品使用指南 (1213 KB)

PRDX5/Peroxiredoxin-5 Protein, Human (His) 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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