PGM2 蛋白, Human (His)

PGM2 Protein is a protein of the alpha-d-phosphohexomutase family. PGM2 has phosphopentomutase activity, that is involved in carbohydrate metabolic process and deoxyribose phosphate catabolic process. The high expression of PGM2 can improve the overall survival rate of patients and have an inhibitory effect on tumors. PGM2 Protein, Human (His) is the recombinant human-derived PGM2 protein, expressed by E. coli , with N-6*His labeled tag.

磷酸戊糖变位酶 2 (PGM2) 是 α-d-磷酸己糖变位酶家族的一种蛋白质。PGM2 具有磷酸戊糖变位酶活性，参与碳水化合物代谢过程和脱氧核糖磷酸分解代谢过程。PGM2 催化核苷分解产物 1-磷酸核糖和 1-磷酸脱氧核糖转化为相应的 5-磷酸戊糖，催化 1-磷酸葡萄糖转化为 6-磷酸葡萄糖，但催化效率较低。它还具有低葡萄糖 1,6-二磷酸合酶活性。PGM2 的高表达可以提高患者的总体生存率，并对肿瘤有抑制作用^[1][2][3]。

The enzyme activity of this recombinant protein is testing in progress, we cannot offer a guarantee yet.

Human

E. coli

N-6*His

AAH10087.1 (M1-D612)

55276  [NCBI]

MAAPEGSGLDEDARLDQETAQWLRWDKNSLTLEAVKRLIAEGNKEELRKCFGARMEFGTAGLRAAMGPGISRMNDLTIIQTTQGFCRYLEKQFSDLKQKGIVISFDARAHPSSGGSSRRFARLAATTFISQGIPVYLFSDITPTPFVPFTVSHLKLCAGIMITASHNPKQDNGYKVYWDNGAQIISPHDKGISQAIEENLEPWPQAWDDSLIDSSPLLHNPSASINNDYFEDLKKYCFHRSVNRETKVKFVHTSVHGVGHSFVQSAFKAFDLVPPEAVPEQKDPDPEFPTVKYPNPEEGKGVLTLSFALADKTKARIVLANDPDADRLAVAEKQDSGEWRVFSGNELGALLGWWLFTSWKEKNQDRSALKDTYMLSSTVSSKILRAIALKEGFHFEETLTGFKWMGNRAKQLIDQGKTVLFAFEEAIGYMCCPFVLDKDGVSAAVISAELASFLATKNLSLSQQLKAIYVEYGYHITKASYFICHDQETIKKLFENLRNYDGKNNYPKACGKFEISAIRDLTTGYDDSQPDKKAVLPTSKSSQMITFTFANGGVATMRTSGTEPKIKYYAELCAPPGNSDPEQLKKELNELVSAIEEHFFQPQKYNLQPKAD

65-75 kDa

Greater than 95% as determined by reducing SDS-PAGE.

无菌粉末.

Lyophilized from a 0.2 μm filtered solution of 20 mM Tris-HCl, 200 mM NaCl, 0.06% Tween80, pH 8.0

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O.

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US;may vary elsewhere.