PILR-beta 蛋白, Human (HEK293, His)

PILR-β is part of a family of paired receptors that play a critical regulatory role in the immune system. PILR-β functions as an activating receptor and is thought to participate in cell signaling by binding to ITAM-bearing adapter molecules, suggesting its role in transmitting immune response signals. PILR-beta Protein, Human (HEK293, His) is the recombinant human-derived PILR-beta protein, expressed by HEK293 , with N-His labeled tag.

PILR-β 是配对受体家族的成员，在免疫系统调节中发挥着至关重要的作用。作为一种激活受体，PILRB 被认为通过与细胞表面上带有 ITAM 的接头分子结合来参与细胞信号传导。这种相互作用表明它参与传递有助于免疫反应和调节的信号。配对受体家族中激活和抑制受体的双重性强调了它们在微调免疫系统活动中的重要性。

Measured by its binding ability in a functional ELISA. Immobilized CL-P1 at 2μg/mL (100μL/well) can bind Biotinylated Human PILR-beta. The ED₅₀ for this effect is 1.808 μg/mL.

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  Measured by its binding ability in a functional ELISA. Immobilized CL-P1 at 2μg/mL (100μL/well) can bind Biotinylated Human PILR-beta. The ED₅₀ for this effect is 1.808 μg/mL.

Human

HEK293

N-6*His

Q9UKJ0-1 (Q20-A189)

29990  [NCBI]

QPGGSTGSGPSYLYGVTQPKHLSASMGGSVEIPFSFYYPWELAIVPNVRISWRRGHFHGQSFYSTRPPSIHKDYVNRLFLNWTEGQESGFLRISNLRKEDQSVYFCRVELDTRRSGRQQLQSIKGTKLTITQAVTTTTTWRPSSTTTIAGLRVTESKGHSESWHLSLDTA

Approximately 30-33 kDa due to the glycosylation

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  Greater than 95% as determined by reducing SDS-PAGE.

无菌粉末

Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O. For long term storage it is recommended to add a carrier protein (0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose).

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.