1. 重组蛋白
  2. Biotinylated Proteins
  3. Placental Lactogen/CSH1 蛋白, Human (Biotinylated, HEK293, His)

Placental Lactogen/CSH1 蛋白, Human (Biotinylated, HEK293, His)

目录号: HY-P77147
产品使用指南

胎盘催乳素/CSH1 蛋白,妊娠专用,协调泌乳、胎儿生长和新陈代谢。其独特的作用模式涉及锌诱导的催乳素受体(PRLR)二聚化,与生长激素受体(GHR)不同。这种特异性和结构多功能性强调了其在复杂的妊娠相关过程和母体生理学中的关键作用。Placental Lactogen/CSH1 蛋白, Human (Biotinylated, HEK293, His) 是重组的 胎盘催乳素/CSH1 蛋白,由 HEK293 表达,带有 C-His 标签。Placental Lactogen/CSH1 蛋白, Human (Biotinylated, HEK293, His) 全长 191 个氨基酸,分子量约为 ~23.7 KDa。

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描述

Placental Lactogen/CSH1 Protein, exclusive to pregnancy, orchestrates lactation, fetal growth, and metabolism. Its unique mode of action involves zinc-induced dimerization of the Prolactin Receptor (PRLR), distinct from the Growth Hormone Receptor (GHR). This specificity and structural versatility underline its pivotal role in intricate pregnancy-related processes and maternal physiology. Placental Lactogen/CSH1 Protein, Human (Biotinylated, HEK293, His) is the recombinant human-derived Placental Lactogen/CSH1 protein, expressed by HEK293 , with C-His labeled tag. The total length of Placental Lactogen/CSH1 Protein, Human (Biotinylated, HEK293, His) is 191 a.a., with molecular weight of ~23.7 KDa.

研究背景

胎盘泌乳原/CSH1 蛋白专门在怀孕期间产生,在协调泌乳、胎儿生长和代谢过程中发挥着关键作用。值得注意的是,它表现出独特的作用模式,因为它不与生长激素受体 (GHR) 相互作用。相反,它的激活完全是通过锌诱导的催乳素受体(PRLR)二聚化介导的。这种独特的机制有助于该蛋白质的特异性,并强调其在与妊娠和母体生理相关的复杂过程中的重要性。值得注意的是,胎盘泌乳素/CSH1 可以单体和二聚体形式存在,突出了其结构的多功能性。

种属

Human

表达系统

HEK293

标签

C-His

蛋白编号

P0DML2 (V27-F217)

基因 ID
蛋白结构
N-term
CSH1 (V27-F217)
Accession # P0DML2
His
C-term
同用名
Chorionic Somatomammotropin Hormone; Placental Lactogen; PL; CSH2
分子量

Approximately 23.7 kDa.

纯度

Greater than 95% as determined by reducing SDS-PAGE.

内毒素含量

<1 EU/μg, determined by LAL method.

文件资料

Placental Lactogen/CSH1 Protein, Human (Biotinylated, HEK293, His) 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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产品名称:
Placental Lactogen/CSH1 Protein, Human (Biotinylated, HEK293, His)
目录号:
HY-P77147
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