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  3. PRAC 蛋白, Human (His-SUMO)

PRAC 蛋白, Human (His-SUMO)

目录号: HY-P73700
产品使用指南

PRAC 蛋白在前列腺、直肠和远端结肠中表达高,在膀胱中表达较弱。它在前列腺癌细胞系中的突出地位表明其与前列腺癌病理学存在潜在联系。组织特异性表达强调了 PRAC 蛋白在正常生理过程和癌症背景中的潜在作用。PRAC 蛋白, Human (His-SUMO) 是重组的 PRAC 蛋白,由 E. coli 表达,带有 N-His, N-SUMO 标签。

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描述

PRAC Protein exhibits high expression in the prostate, rectum, and distal colon, with weaker expression in the bladder. Its prominence in prostate cancer cell lines suggests a potential link to prostate cancer pathology. The tissue-specific expression emphasizes PRAC Protein's potential roles in normal physiological processes and cancer contexts. PRAC Protein, Human (His-SUMO) is the recombinant human-derived PRAC protein, expressed by E. coli , with N-His, N-SUMO labeled tag.

研究背景

PRAC 蛋白因其在前列腺、直肠和远端结肠中的高表达水平而脱颖而出,而在膀胱中的表达相对较弱。值得注意的是,这种蛋白质在前列腺癌细胞系中尤其突出,表明与前列腺癌病理学存在潜在关联。这些组织中的差异表达模式表明 PRAC 蛋白可能发挥的组织特异性作用,强调了其在正常生理过程和癌症相关环境中的潜在重要性。

种属

Human

表达系统

E. coli

标签

N-His;N-SUMO

蛋白编号

Q96KF2/NP_115767.1 (M1-P57)

基因 ID
蛋白结构
N-term
His-SUMO
PRAC (M1-F57)
Accession # Q96KF2/NP_115767.1
C-term
同用名
Small nuclear protein PRAC1; PRAC1; C17orf92; PRAC
分子量

Approximately 25 kDa

纯度

Greater than 85% as determined by reducing SDS-PAGE.

内毒素含量

<1 EU/μg, determined by LAL method.

文件资料

PRAC Protein, Human (His-SUMO) 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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产品名称:
PRAC Protein, Human (His-SUMO)
目录号:
HY-P73700
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