Profilin-2 蛋白, Human

Profilin-2 protein is a key player in protein folding. It specifically binds to cytosolic chaperone protein (c-CPN) and promotes the transfer of target proteins. It also interacts with nascent polypeptide chains, helping unnatural proteins fold correctly in various competing pathways. Profilin-2 Protein, Human is the recombinant human-derived Profilin-2 protein, expressed by E. coli , with tag free.

PFDN2 是蛋白质折叠中的关键参与者，对胞质伴侣蛋白 (c-CPN) 表现出特异性结合亲和力，促进目标蛋白质向该复合物的转移。此外，PFDN2 与新生多肽链相互作用，促进其在存在各种非天然蛋白质竞争途径的环境中正确折叠。PFDN2的异六聚体结构包含两个PFD-α型和四个PFD-β型亚基。此外，PFDN2 是 PAQosome 复合物的一个组成部分，与其他成员（如 RUVBL1、RUVBL2、RPAP3、PIH1D1、PFDN6、PDRG1、UXT、URI1、ASDURF、POLR2E 和 DNAAF10/WDR92）在多种蛋白质复合物的生物合成中合作。值得注意的是，PFDN2 和 URI1 之间的相互作用是磷酸化依赖性的，并表现出生长依赖性模式，突出了细胞过程中涉及的复杂调节机制。

Human

E. coli

Tag Free

P35080-1 (M1-F140)

5217  [NCBI]

MAGWQSYVDNLMCDGCCQEAAIVGYCDAKYVWAATAGGVFQSITPIEIDMIVGKDREGFFTNGLTLGAKKCSVIRDSLYVDGDCTMDIRTKSQGGEPTYNVAVGRAGRVLVFVMGKEGVHGGGLNKKAYSMAKYLRDSGF

Approximately 14.0 kDa

Greater than 95% as determined by reducing SDS-PAGE.

<1 EU/μg, determined by LAL method.