PS-beta-G-5 蛋白, Human (HEK293, His)

PS-beta-G-5 Protein, a major secreted protein group synthesized by placental syncytiotrophoblast cells, promotes the selective activation of macrophages and is associated with the transition from inflammatory Th1-mediated immune response to anti-inflammatory Th2-mediated immune response in vitro and in vivo. PS-beta-G-5 Protein, Human (HEK293, His) is the recombinant human-derived PS-beta-G-5 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of PS-beta-G-5 Protein, Human (HEK293, His) is 301 a.a., with molecular weight of ~50.0 kDa.

PSG 是胎盘合体滋养细胞合成的主要分泌蛋白群，促进巨噬细胞的选择性活化，与体外和体内由炎症性 Th1-介导的免疫反应向抗炎性 Th2 介导的免疫反应转变有关。与组蛋白和非组蛋白相关的赖氨酸乙酰化可上调 PSG 基因的表达。KLF4 和 Sp1 对 PSG-5 启动子有激活作用。

Human

HEK293

C-6*His

AAH12607.1 (Q35-I335)

5673  [NCBI]

QVTIEALPPKVSEGKDVLLLVHNLPQNLAGYIWYKGQLMDLYHYITSYVVDGQINIYGPAYTGRETVYSNASLLIQNVTREDAGSYTLHIIKRGDRTRGVTGYFTFNLYLKLPKPYITINNSKPRENKDVLAFTCEPKSENYTYIWWLNGQSLPVSPRVKQPIENRILILPSVTRNETGPYECEIRDRDGGMHSDPVTLNVLYGPDLPSIYPSFTYYRSGENLYLSCFAESNPPAEYFWTINGKFQQSGQKLSIPQITTKHRGLYTCSVRNSATGKESSKSMTVEVSAPSGIGRLPLLNPI

Approximately 50.0 kDa

Greater than 95% as determined by reducing SDS-PAGE.

无菌粉末.

Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.4.

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O. For long term storage it is recommended to add a carrier protein (0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose).

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US;may vary elsewhere.