1. 重组蛋白
  2. Enzymes & Regulators
  3. Hydrolases (EC 3)
  4. PTP4A1 蛋白, Human (His)

PTP4A1 蛋白, Human (His)

目录号: HY-P701032
产品使用指南

PTP4A1蛋白是一种活性酪氨酸磷酸酶,不仅刺激有丝分裂从G1期进展到S期,而且在分化上皮组织的发育和维持中发挥着至关重要的作用。其多功能贡献延伸至细胞分化,通过增强增殖、运动性和侵袭活性来深刻影响细胞行为。PTP4A1 蛋白, Human (His) 是重组的 PTP4A1 蛋白,由 E. coli 表达,带有 N-His 标签。PTP4A1 蛋白, Human (His) 全长 170 个氨基酸,分子量为 20.56 kDa。

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描述

The PTP4A1 protein is an active tyrosine phosphatase that not only stimulates the G1 to S phase progression of mitosis but also plays a crucial role in the development and maintenance of differentiated epithelial tissues. Its multifunctional contribution extends to cell differentiation, profoundly affecting cell behavior by enhancing proliferation, motility, and invasive activity. PTP4A1 Protein, Human (His) is the recombinant human-derived PTP4A1 protein, expressed by E. coli , with N-His labeled tag. The total length of PTP4A1 Protein, Human (His) is 170 a.a., with molecular weight of 20.56 kDa.

研究背景

PTP4A1 蛋白是一种动态蛋白酪氨酸磷酸酶,是刺激有丝分裂期间从 G1 进入 S 期的关键调节因子。除了其有丝分裂作用之外,PTP4A1 还参与分化上皮组织的发育和维持,强调了其对细胞分化的多功能贡献。值得注意的是,PTP4A1 对细胞行为具有深远的影响,可增强细胞增殖、运动和侵袭活性。在癌症中,PTP4A1 发挥着关键作用,促进转移。其多方面功能凸显了 PTP4A1 在协调多种细胞过程中的重要作用,对正常组织发育以及与癌症进展和转移相关的病理状况都有影响。

种属

Human

表达系统

E. coli

标签

N-His

蛋白编号

Q93096 (M1-C170)

基因 ID
蛋白结构
N-term
His
PTP4A1 (M1-C170)
Accession # Q93096
C-term
同用名
PTP4A1; PTP(CAAXI); PRL-1; PRL1; PTPCAAX1;
分子量

20.56 kDa

纯度

Greater than 95% as determined by reducing SDS-PAGE.

内毒素含量

<1 EU/μg, determined by LAL method.

文件资料

PTP4A1 Protein, Human (His) 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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HY-P701032
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