1. 重组蛋白
  2. Cytokines and Growth Factors
  3. TNF Superfamily
  4. TNF Receptor Superfamily
  5. RELT TNF Receptor
  6. RELT 蛋白, Human (HEK293, Fc)

RELT 蛋白, Human (HEK293, Fc)

目录号: HY-P71258
COA 产品使用指南

RELT 蛋白可能在细胞凋亡中发挥作用,表明它参与了程序性细胞死亡的复杂细胞过程。当过度表达时,RELT 会激活 MAPK14/p38 和 MAPK8/JNK MAPK 级联,影响关键信号通路。RELT 蛋白, Human (HEK293, Fc) 是重组的 RELT 蛋白,由 HEK293 表达,带有 C-hFc 标签。RELT 蛋白, Human (HEK293, Fc) 全长 135 个氨基酸,分子量为 40-54 kDa。

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     可免费申领三个不同产品的试用装。

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规格 价格 是否有货 数量
10 μg ¥900 In-stock
50 μg ¥2500 In-stock
100 μg   询价  

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描述

RELT protein may play a role in apoptosis, suggesting its involvement in the complex cellular process of programmed cell death. When overexpressed, RELT activates the MAPK14/p38 and MAPK8/JNK MAPK cascades, affecting key signaling pathways. RELT Protein, Human (HEK293, Fc) is the recombinant human-derived RELT protein, expressed by HEK293 , with C-hFc labeled tag. The total length of RELT Protein, Human (HEK293, Fc) is 135 a.a., with molecular weight of 40-54 kDa.

研究背景

RELT 蛋白可能在细胞凋亡中发挥作用,表明它参与了程序性细胞死亡的复杂细胞过程。当过度表达时,RELT 会诱导 MAPK14/p38 和 MAPK8/JNK MAPK 级联的激活,表明其对与细胞反应相关的关键信号通路有影响。此外,RELT 被认为在牙釉质形成中发挥作用,有助于牙齿发育的复杂过程。该蛋白与各种伙伴相互作用,包括 TRAF1、RELL1、RELL2、OXSR1、PLSCR1 和 STK39,强调了其在分子相互作用中的多功能性,并表明其可能参与细胞凋亡以外的多种细胞功能,包括信号转导和发育过程。

种属

Human

表达系统

HEK293

标签

C-hFc

蛋白编号

Q969Z4 (S26-A160)

基因 ID
蛋白结构
N-term
RELT (S26-A160)
Accession # Q969Z4
hFc
C-term
同用名
Tumor necrosis factor receptor superfamily member 19L; TNFRSF19L; Receptor expressed in lymphoid tissues; RELT
氨基酸序列

STTLWQCPPGEEPDLDPGQGTLCRPCPPGTFSAAWGSSPCQPHARCSLWRRLEAQVGMATRDTLCGDCWPGWFGPWGVPRVPCQPCSWAPLGTHGCDEWGRRARRGVEVAAGASSGGETRQPGNGTRAGGPEETA

分子量

40-54 kDa

纯度

Greater than 90% as determined by reducing SDS-PAGE.

性状

溶液.

组分

Supplied as a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.2.

内毒素含量

<1 EU/μg, determined by LAL method.

保存条件 & 期限

Stored at -80°C for 1 year. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.

运输条件

Shipping with dry ice.

文件资料
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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  • 重组蛋白稀释计算器

  • 比活力计算器

The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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产品名称:
RELT Protein, Human (HEK293, Fc)
目录号:
HY-P71258
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