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  4. SLITRK1 蛋白, Human (HEK293, His)

SLITRK1 蛋白, Human (HEK293, His)

目录号: HY-P76078
产品使用指南

SLITRK1 蛋白对于突触发生至关重要，可促进兴奋性突触分化和突触成熟。它的作用延伸到促进神经元树突的生长，强调了它在神经元发育中的重要性。SLITRK1 蛋白, Human (HEK293, His) 是重组的 SLITRK1 蛋白，由 HEK293 表达，带有 C-His 标签。SLITRK1 蛋白, Human (HEK293, His) 全长 599 个氨基酸，分子量为 105-115 kDa。

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描述

The SLITRK1 protein is critical in synaptogenesis, promoting excitatory synaptic differentiation and synaptic maturation. Its effects extend to enhancing the growth of neuronal dendrites, emphasizing its importance in neuronal development. SLITRK1 Protein, Human (HEK293, His) is the recombinant human-derived SLITRK1 protein, expressed by HEK293 , with C-His labeled tag. The total length of SLITRK1 Protein, Human (HEK293, His) is 599 a.a., with molecular weight of 105-115 kDa.
研究背景

SLITRK1 在突触发生中发挥着至关重要的作用，积极促进兴奋性突触的分化，其参与突触成熟就证明了这一点。此外，SLITRK1 有助于增强神经元树突生长，强调其在神经元发育和形态中的重要性。该蛋白质能够形成同型二聚体，这种二聚化过程特别依赖于重复 LRR 2 结构域的存在。此外，SLITRK1 与 14-3-3 蛋白家族的各个成员相互作用，包括 YWHAB、YWHAE、YWHAG、YWHAH、SFN、YWHAQ 和 YWHAZ，表明这些相互作用介导潜在的调节作用和细胞功能。
种属

Human
表达系统

HEK293
标签

C-His
蛋白编号

Q96PX8 (N18-S616)
基因 ID
蛋白结构
N-term
SLITRK1 (N18-S616)
Accession # Q96PX8
His
C-term
同用名
SLIT and NTRK-like protein 1; Leucine-rich repeat-containing protein 12; SLITRK1; KIAA1910; LRRC12
分子量

105-115 kDa
纯度

Greater than 95% as determined by reducing SDS-PAGE
内毒素含量

<1 EU/μg, determined by LAL method.
文件资料
产品使用指南 (1213 KB)

SLITRK1 Protein, Human (HEK293, His) 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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