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  4. SLITRK4 蛋白, Human (HEK293, His)

SLITRK4 蛋白, Human (HEK293, His)

目录号: HY-P77207
产品使用指南

SLITRK4 蛋白在突触发生中至关重要，可促进突触分化和突触成熟。相反，它抑制神经突生长，表明在神经元形态中具有调节作用。SLITRK4 通过其 LRR 1 和 2 重复序列与 PTPRD 相互作用，表明其在调节 PTPRD 的活性或功能中具有潜在作用，PTPRD 是一种与神经发育和突触可塑性相关的受体型蛋白酪氨酸磷酸酶。SLITRK4 蛋白, Human (HEK293, His) 是重组的 SLITRK4 蛋白，由 HEK293 表达，带有 C-His 标签。SLITRK4 蛋白, Human (HEK293, His) 全长 598 个氨基酸，分子量约为 ~85 kDa。

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描述

SLITRK4 Protein is pivotal in synaptogenesis, promoting synapse differentiation and synaptic maturation. Conversely, it suppresses neurite outgrowth, indicating a regulatory role in neuronal morphology. Interacting with PTPRD through its LRR 1 and 2 repeats, SLITRK4 suggests a potential role in modulating the activity or function of PTPRD, a receptor-type protein tyrosine phosphatase associated with neural development and synaptic plasticity. SLITRK4 Protein, Human (HEK293, His) is the recombinant human-derived SLITRK4 protein, expressed by HEK293 , with C-His labeled tag. The total length of SLITRK4 Protein, Human (HEK293, His) is 598 a.a., with molecular weight of ~85 kDa.
研究背景

SLITRK4 在突触发生中发挥着至关重要的作用，积极促进突触的分化，其参与突触成熟就证明了这一点。相反，SLITRK4 抑制神经突生长，表明神经元形态具有调节功能。该蛋白通过其 LRR 1 和 2 重复序列与 PTPRD 相互作用，表明在调节 PTPRD 的活性或功能中具有潜在作用，PTPRD 是一种受体型蛋白酪氨酸磷酸酶，因其参与神经发育和突触可塑性而闻名。
种属

Human
表达系统

HEK293
标签

C-His
蛋白编号

Q8IW52 (D19-P616)
基因 ID
蛋白结构
N-term
SLITRK4 (D19-P616)
Accession # Q8IW52
His
C-term
同用名
SLIT and NTRK-like protein 4; SLITRK4
分子量

Approximately 85 kDa
纯度

Greater than 90% as determined by reducing SDS-PAGE
内毒素含量

<1 EU/μg, determined by LAL method.
文件资料
产品使用指南 (1213 KB)

SLITRK4 Protein, Human (HEK293, His) 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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