TMPRSS1/HPN 蛋白, Human (HEK293, His)

TMPRSS1/HPN is a serine protease that cleaves extracellular substrates and is involved in the proteolytic processing of growth factors such as HGF and MST1/HGFL. In addition to growth factor regulation, TMPRSS1/HPN is also critical for cell growth and morphology maintenance. TMPRSS1/HPN Protein, Human (HEK293, His) is the recombinant human-derived TMPRSS1/HPN protein, expressed by HEK293 , with C-His labeled tag. The total length of TMPRSS1/HPN Protein, Human (HEK293, His) is 373 a.a., with molecular weight of 18-22 kDa&30 kDa.

TMPRSS1/HPN 是一种丝氨酸蛋白酶，参与各种细胞外底物的裂解，有助于生长因子（如 HGF 和 MST1/HGFL）的蛋白水解加工。除了在生长因子调节中的作用之外，TMPRSS1/HPN 在细胞生长和细胞形态的维持中也发挥着重要作用。此外，这种蛋白酶还参与 ACE2 的蛋白水解过程，强调其参与关键的细胞途径。值得注意的是，TMPRSS1/HPN 介导尿 UMOD 的蛋白水解裂解，这是 UMOD 聚合所必需的过程，强调了其在调节各种生物过程中的多功能作用。

Immobilized Human HPN, His Tag at 2 μg/mL (100 μl/Well) on the plate. Dose response curve for Anti-HPN Antibody, hFc Tag with the EC₅₀ of ≤20.0 ng/mL determined by ELISA.

Human

HEK293

C-His

P05981 (R45-L417)

3249  [NCBI]

18-22 kDa&30 kDa

Greater than 95% as determined by Tris-Bis PAGE.

无菌粉末.

Lyophilized from 0.22 μm filtered solution in 20 mM NaAc,150 mM NaCl (pH 5.0). Normally 8% trehalose is added as protectant before lyophilization.

<1 EU/μg, determined by LAL method.

Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in 20 mM NaAc,150 mM NaCl (pH 5.0).

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.