Transferrin R2 蛋白, Mouse (HEK293, mFc)

The transferrin R2 protein is a key player in iron-independent cellular uptake of transferrin-bound iron, underscoring its role in delicate iron metabolism. Among other things, it may have crucial effects on liver cell function and red blood cell differentiation. Transferrin R2 Protein, Mouse (HEK293, mFc) is the recombinant mouse-derived Transferrin R2 protein, expressed by HEK293 , with N-mFc labeled tag.

转铁蛋白 R2 蛋白是细胞摄取转铁蛋白结合铁的关键参与者，展示了其在铁代谢中的作用。有趣的是，这个过程以非铁依赖性方式发生，表明铁获取的微妙和受调节的机制。除了参与铁代谢之外，转铁蛋白 R2 可能在肝细胞功能和红细胞分化中发挥关键作用，强调了其在各种细胞过程中的重要性。转铁蛋白 R2 促进这些功能的具体分子机制仍有待充分阐明，这促使进一步研究其功能意义以及对铁相关途径、肝细胞和红细胞发育的调节影响。全面的研究对于揭示转铁蛋白 R2 发挥作用的精确分子途径并了解其在细胞和生理过程中的更广泛影响至关重要。

Mouse

HEK293

N-mFc

Q9JKX3-1 (R103-F798)

50765  [NCBI]

RGSCQACGDSVLVVDEDVNPEDSGRTTLYWSDLQAMFLRFLGEGRMEDTIRLTSLRERVAGSARMATLVQDILDKLSRQKLDHVWTDTHYVGLQFPDPAHANTLHWVDADGSVQEQLPLEDPEVYCPYSATGNATGKLVYAHYGRSEDLQDLKAKGVELAGSLLLVRVGITSFAQKVAVAQDFGAQGVLIYPDPSDFSQDPHKPGLSSHQAVYGHVHLGTGDPYTPGFPSFNQTQFPPVESSGLPSIPAQPISADIADQLLRKLTGPVAPQEWKGHLSGSPYRLGPGPDLRLVVNNHRVSTPISNIFACIEGFAEPDHYVVIGAQRDAWGPGAAKSAVGTAILLELVRTFSSMVSNGFRPRRSLLFISWDGGDFGSVGATEWLEGYLSVLHLKAVVYVSLDNSVLGDGKFHAKTSPLLVSLIENILKQVDSPNHSGQTLYEQVALTHPSWDAEVIQPLPMDSSAYSFTAFAGVPAVEFSFMEDDRVYPFLHTKEDTYENLHKMLRGRLPAVVQAVAQLAGQLLIRLSHDHLLPLDFGRYGDVVLRHIGNLNEFSGDLKERGLTLQWVYSARGDYIRAAEKLRKEIYSSERNDERLMRMYNVRIMRVEFYFLSQYVSPADSPFRHIFLGQGDHTLGALVDHLRMLRADGSGAASSRLTAGLGFQESRFRRQLALLTWTLQGAANALSGDVWNIDNNF

Approximately 116 kDa

Greater than 95% as determined by reducing SDS-PAGE.

无菌粉末

Lyophilized a 0.22 μm filtered solution of PBS, 6% Trehalose, pH 7.4.

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O. For long term storage it is recommended to add a carrier protein (0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose).

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.