1. Gene
  2. Tfr2 - transferrin receptor 2 Gene

Tfr2 - transferrin receptor 2 Gene

种属: Mus musculus

同用名: Trfr2

基因 ID: 50765 | 基因类型: protein coding

关于 Tfr2

功能概要

Predicted to enable co-receptor binding activity and Transferrin Receptor activity. Acts upstream of or within iron ion homeostasis. Part of HFE-transferrin receptor complex. Is expressed in liver lobe; mesonephros; and urinary system. Used to study hemochromatosis type 3. Human ortholog(s) of this gene implicated in hemochromatosis and hemochromatosis type 3. Orthologous to human TFR2 (Transferrin Receptor 2). [provided by Alliance of Genome Resources, Apr 2022]

Tfr2 基因产物(5)

mRNA Protein Name
NM_001289507.2 NP_001276436.2 transferrin receptor protein 2
NM_001289509.1 NP_001276438.1 transferrin receptor protein 2
NM_001289511.1 NP_001276440.1 transferrin receptor protein 2
NM_001359206.1 NP_001346135.1 transferrin receptor protein 2
NM_015799.4 NP_056614.3 transferrin receptor protein 2
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
16893896 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within multicellular organismal-level iron ion homeostasis IMP
IMP: 通过突变表型推断
22960056 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
part of HFE-transferrin receptor complex IDA
IDA: 通过直接分析推断
16893896 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

transferrin receptor protein 2

重组 Tfr2 蛋白

目录号 产品名 蛋白编号 纯度
HY-P78783 Transferrin R2 Protein, Mouse (HEK293, mFc) Q9JKX3-1 (R103-F798) ≥95%

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Tfr2 NCBI NCBI:7036