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  4. ULBP2/NKG2DL2 蛋白, Human (HEK293, hFc)

ULBP2/NKG2DL2 蛋白, Human (HEK293, hFc)

目录号: HY-P701055
产品使用指南

NKG2DL2 蛋白激活 KLRK1/NKG2D 受体，促进自然杀伤细胞的细胞毒性。重要的是，研究结果证实，它不结合 β2-微球蛋白。ULBP2/NKG2DL2 蛋白, Human (HEK293, hFc) 是重组的 ULBP2/NKG2DL2 蛋白，由 HEK293 表达，带有 C-hFc 标签。ULBP2/NKG2DL2 蛋白, Human (HEK293, hFc) 全长 191 个氨基酸，分子量为 55-65 kDa。

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描述

NKG2DL2 Protein activates KLRK1/NKG2D receptor, promoting natural killer cell cytotoxicity. Importantly, it does not bind beta2-microglobulin, confirmed by research findings. ULBP2/NKG2DL2 Protein, Human (HEK293, hFc) is the recombinant human-derived ULBP2/NKG2DL2 protein, expressed by HEK293 , with C-hFc labeled tag. The total length of ULBP2/NKG2DL2 Protein, Human (HEK293, hFc) is 191 a.a., with molecular weight of 55-65 kDa.
研究背景

NKG2DL2 蛋白通过结合并激活 KLRK1/NKG2D 受体发挥作用，从而促进自然杀伤细胞的细胞毒性。它与 KLRK1/NKG2D 的相互作用已被记录。值得注意的是，研究结果表明，该蛋白质不表现出与 β2 微球蛋白的结合亲和力。
种属

Human
表达系统

HEK293
标签

C-hFc
蛋白编号

Q9BZM5 (G26-S216)
基因 ID
蛋白结构
N-term
ULBP2 (G26-S216)
Accession # Q9BZM5
hFc
C-term
同用名
ALCAN-alpha; N2DL2; NKG2DL2; RAET1H; RAET1L; ULBP2; ULBP-2/5/6; NKG2D ligand 2
分子量

55-65 kDa
纯度

Greater than 95% as determined by reducing SDS-PAGE.
内毒素含量

<1 EU/μg, determined by LAL method.
文件资料
产品使用指南 (1213 KB)

ULBP2/NKG2DL2 Protein, Human (HEK293, hFc) 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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