VAMP3 蛋白, Human (His)

VAMP3 protein is an important SNARE protein that promotes vesicle transport from late endosomes to the trans-Golgi network. Its interaction with BVES, mediated by its C-terminal cytoplasmic tail, is crucial in this process. VAMP3 Protein, Human (His) is the recombinant human-derived VAMP3 protein, expressed by E. coli , with N-His labeled tag. The total length of VAMP3 Protein, Human (His) is 77 a.a., with molecular weight of ~11 kDa.

VAMP3 是一种关键的 SNARE 蛋白，在协调从晚期内体到跨高尔基体网络的囊泡运输中发挥着关键作用。与 BVES 的相互作用通过其 C 端胞质尾部促进，在这一运输过程中具有重要意义。此外，VAMP3与BCAP31合作，有助于VAMP3从内质网的有效输出。值得注意的是，与 BAIAP3 的关联受到钙的调节，揭示了微妙的调节方面。除了这些相互作用之外，VAMP3 还与 PICALM 结合，进一步强调了控制其多种细胞功能的复杂分子关联网络。

Human

E. coli

N-10*His

Q15836 (M1-K77)

9341  [NCBI]

MSTGPTAATGSNRRLQQTQNQVDEVVDIMRVNVDKVLERDQKLSELDDRADALQAGASQFETSAAKLKRKYWWKNCK

Approximately 12 kDa

• 
  Greater than 95% as determined by reducing SDS-PAGE.

无菌粉末

Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4, 5% trehalose, 5% mannitol and 0.01% Tween80.

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O. For long term storage it is recommended to add a carrier protein (0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose).

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.