VAMP3 - vesicle associated membrane protein 3 Gene

中文名称：囊泡相关膜蛋白 3

种属: Homo sapiens

同用名: CEB

关于 VAMP3

功能概要

Synaptobrevins/VAMPs、syntaxins 和 25-kD 突触体相关蛋白是参与突触小泡与突触前膜的对接和/或融合的蛋白质复合物的主要成分。该基因是囊泡相关膜蛋白 (VAMP) /synaptobrevin 家族的成员。由于其与其他已知 VAMP 的高度同源性、其广泛的组织分布及其亚细胞定位，该基因编码的蛋白质被证明是啮齿动物 cellubrevin 的人类等效物。在血小板中，蛋白质位于一个隔室中，该隔室在钙或凝血酶刺激下不会移动到质膜上。[RefSeq 提供，2008 年 7 月]

Synaptobrevins/VAMPs, syntaxins, and the 25-kD synaptosomal-associated protein are the main components of a protein complex involved in the docking and/or fusion of synaptic vesicles with the presynaptic membrane. This gene is a member of the vesicle-associated membrane protein (VAMP)/synaptobrevin family. Because of its high homology to Other known VAMPs, its broad tissue distribution, and its subcellular localization, the protein encoded by this gene was shown to be the human equivalent of the rodent cellubrevin. In platelets the protein resides on a compartment that is not mobilized to the plasma membrane on calcium or Thrombin stimulation. [provided by RefSeq, Jul 2008]