1. Gene
  2. BCL2L13 - BCL2 like 13 Gene

BCL2L13 - BCL2 like 13 Gene

中文名称:BCL2 样 13

种属: Homo sapiens

同用名: MIL1; BCL-RAMBO; Bcl2-L-13

基因 ID: 23786 | 基因类型: protein coding

关于 BCL2L13

Cytogenetic location: 22q11.21 Genomic coordinates (GRCh38): 22:17,628,877-17,730,855 (from NCBI)

This gene has 17 transcripts (splice variants) and 206 orthologues. Ubiquitous expression in fat (RPKM 9.5), adrenal (RPKM 9.0) and 25 other tissues.

功能概要

该基因编码具有保守 B 细胞淋巴瘤 2 同源基序的线粒体定位蛋白。编码蛋白的过度表达导致细胞凋亡。已观察到该基因的可变剪接转录物变体。[RefSeq 提供,2012 年 7 月]

This gene encodes a mitochondrially-localized protein with conserved B-cell lymphoma 2 homology motifs. Overexpression of the encoded protein results in Apoptosis. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Jul 2012]

BCL2L13 基因产物(12)

mRNA Protein Name
NM_001270726.1 NP_001257655.1 bcl-2-like protein 13 isoform b
NM_001270727.1 NP_001257656.1 bcl-2-like protein 13 isoform c
NM_001270728.2 NP_001257657.1 bcl-2-like protein 13 isoform d
NM_001270729.2 NP_001257658.1 bcl-2-like protein 13 isoform e
NM_001270730.2 NP_001257659.1 bcl-2-like protein 13 isoform e
NM_001270731.2 NP_001257660.1 bcl-2-like protein 13 isoform e
NM_001270732.2 NP_001257661.1 bcl-2-like protein 13 isoform f
NM_001270733.2 NP_001257662.1 bcl-2-like protein 13 isoform g
NM_001270734.2 NP_001257663.1 bcl-2-like protein 13 isoform h
NM_001270735.2 NP_001257664.1 bcl-2-like protein 13 isoform i
NM_001363824.1 NP_001350753.1 bcl-2-like protein 13 isoform j
NM_015367.4 NP_056182.2 bcl-2-like protein 13 isoform a
基因本体论
  • 分子功能
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
16189514 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in membrane IDA
IDA: 通过直接分析推断
11262395 GOA
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断

BCL2L13 蛋白结构

Bcl-2

Bcl-2: Apoptosis regulator proteins, Bcl-2 family (104 - 200)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 485 a.a.
蛋白主名 其他名称

bcl-2-like protein 13

BCL2-like 13 (apoptosis facilitator)

BCL2L13 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
BCL2L13 Q9BXK5 VAMP4 Homo sapiens O75379-2
Validated Y2H
25416956
种属内
BCL2L13 Q9BXK5 VAMP4 Homo sapiens O75379-2
Y2H Array
25416956
种属内
BCL2L13 Q9BXK5 VAMP4 Homo sapiens O75379-2
Y2H Prey Pooling
25416956
种属内
BCL2L13 Q9BXK5 BET1 Homo sapiens Q53XK0
Y2H Prey Pooling
25416956
种属内
BCL2L13 Q9BXK5 TMEM128 Homo sapiens Q5BJH2
Y2H Prey Pooling
25416956
种属内
BCL2L13 Q9BXK5 TMEM128 Homo sapiens Q5BJH2
Validated Y2H
25416956
种属内
BCL2L13 Q9BXK5 TMEM128 Homo sapiens Q5BJH2
Y2H Array
25416956
种属内
BCL2L13 Q9BXK5 DEFB127 Homo sapiens Q9H1M4
Validated Y2H
32296183
种属内
BCL2L13 Q9BXK5 TMEM242 Homo sapiens Q9NWH2
Validated Y2H
32296183
种属内
BCL2L13 Q9BXK5 TMEM242 Homo sapiens Q9NWH2
Y2H Prey Pooling
32296183
种属内
BCL2L13 Q9BXK5 TMEM242 Homo sapiens Q9NWH2
Y2H Array
32296183
种属内
BCL2L13 Q9BXK5 NINJ2 Homo sapiens Q9NZG7
Y2H Array
25416956
种属内
BCL2L13 Q9BXK5 NINJ2 Homo sapiens Q9NZG7
Y2H Prey Pooling
25416956
种属内
BCL2L13 Q9BXK5 KIF1B Homo sapiens O60333-2
Y2H Array
32814053
种属内
BCL2L13 Q9BXK5 KIF1B Homo sapiens O60333-2
Y2H Pooling
32814053
种属内
BCL2L13 Q9BXK5 KIF1B Homo sapiens O60333-2
Validated Y2H
32814053
种属内
BCL2L13 Q9BXK5 AIG1 Homo sapiens Q9NVV5-2
Validated Y2H
32296183
种属内
BCL2L13 Q9BXK5 TNMD Homo sapiens Q9H2S6-2
Validated Y2H
32296183
种属内
BCL2L13 Q9BXK5 LPAR3 Homo sapiens Q9UBY5
Validated Y2H
32296183
种属内
BCL2L13 Q9BXK5 TM6SF2 Homo sapiens Q9BZW4
Validated Y2H
32296183
种属内
BCL2L13 Q9BXK5 CRB3 Homo sapiens Q9BUF7-2
Y2H Prey Pooling
32296183
种属内
BCL2L13 Q9BXK5 CRB3 Homo sapiens Q9BUF7-2
Y2H Array
32296183
种属内
BCL2L13 Q9BXK5 FAM210B Homo sapiens Q96KR6
Y2H Array
32296183
种属内
BCL2L13 Q9BXK5 FAM210B Homo sapiens Q96KR6
Y2H Prey Pooling
32296183
种属内
BCL2L13 Q9BXK5 TMEM14C Homo sapiens Q9P0S9
Validated Y2H
32296183
种属内
BCL2L13 Q9BXK5 TMEM86B Homo sapiens Q8N661
Y2H Array
32296183
种属内
BCL2L13 Q9BXK5 TMEM86B Homo sapiens Q8N661
Y2H Prey Pooling
32296183
种属内
BCL2L13 Q9BXK5 TMUB2 Homo sapiens Q71RG4
Validated Y2H
25416956
种属内
BCL2L13 Q9BXK5 TMUB2 Homo sapiens Q71RG4
Y2H Array
25416956
种属内
BCL2L13 Q9BXK5 ERG28 Homo sapiens Q9UKR5
Validated Y2H
32296183
种属内
BCL2L13 Q9BXK5 WFS1 Homo sapiens O76024
Y2H Array
32814053
种属内
BCL2L13 Q9BXK5 WFS1 Homo sapiens O76024
Y2H Pooling
32814053
种属内
BCL2L13 Q9BXK5 WFS1 Homo sapiens O76024
Validated Y2H
32814053
种属内
BCL2L13 Q9BXK5 VAMP3 Homo sapiens Q15836
Y2H Prey Pooling
25416956
种属内
BCL2L13 Q9BXK5 VAMP3 Homo sapiens Q15836
Validated Y2H
25416956
种属内
BCL2L13 Q9BXK5 TMEM51 Homo sapiens Q9NW97
Y2H Prey Pooling
32296183
种属内
BCL2L13 Q9BXK5 TMEM51 Homo sapiens Q9NW97
Validated Y2H
32296183
种属内
BCL2L13 Q9BXK5 TMEM51 Homo sapiens Q9NW97
Y2H Array
32296183
种属内
BCL2L13 Q9BXK5 STX8 Homo sapiens Q9UNK0
Validated Y2H
32296183
种属内
BCL2L13 Q9BXK5 SOD1 Homo sapiens P00441
Anti Tag CoIP
28514442
种属内
BCL2L13 Q9BXK5 SOD1 Homo sapiens P00441
Anti Tag CoIP
33961781
种属间: 跨种属相互作用 种属内: 同种属相互作用

直系同源

种属 基因名 来源 基因 ID
Canis familiaris BCL2L13 VGNC VGNC:38409
Macaca mulatta BCL2L13 VGNC VGNC:84544
Felis catus BCL2L13 VGNC VGNC:60084
Rattus norvegicus BCL2L13 RGD RGD:1306985
Mus musculus BCL2L13 MGD MGI:2136959
Bos taurus BCL2L13 VGNC VGNC:56193