MGST3 - microsomal glutathione S-transferase 3 Gene

中文名称：微粒体谷胱甘肽 S-转移酶 3

种属: Homo sapiens

同用名: GST-III

关于 MGST3

功能概要

该基因编码 MAPEG (花生酸和谷胱甘肽代谢中的膜相关蛋白) 蛋白家族的成员。该家族的成员参与白三烯和前列腺素 E (炎症的重要介质) 的产生。该基因编码一种酶，该酶催化白三烯 A4 与还原型谷胱甘肽结合，产生白三烯 C4。这种酶还表现出谷胱甘肽依赖性过氧化物酶对脂质氢过氧化物的活性。[RefSeq 提供，2011 年 5 月]

This gene encodes a member of the MAPEG (Membrane Associated Proteins in Eicosanoid and Glutathione metabolism) protein family. Members of this family are involved in the production of leukotrienes and prostaglandin E, important mediators of inflammation. This gene encodes an Enzyme which catalyzes the conjugation of leukotriene A4 and reduced glutathione to produce leukotriene C4. This Enzyme also demonstrates glutathione-dependent peroxidase activity towards lipid hydroperoxides.[provided by RefSeq, May 2011]