SLC2A5 - solute carrier family 2 member 5 Gene

中文名称：溶质载体家族 2 成员 5

种属: Homo sapiens

同用名: GLUT5; GLUT-5

基因 ID: 6518 | 基因类型: protein coding

关于 SLC2A5

Cytogenetic location: 1p36.23 Genomic coordinates (GRCh38): 1:9,035,106-9,094,195 (from NCBI)

This gene has 10 transcripts (splice variants), 259 orthologues and 13 paralogues. Biased expression in duodenum (RPKM 33.7), small intestine (RPKM 25.5) and 8 other tissues.

功能概要

该基因编码的蛋白质是负责小肠摄取果糖的果糖转运体。由于高饮食果糖摄入量，所编码的蛋白质也是血压升高所必需的。[RefSeq 提供，2016 年 6 月]

The protein encoded by this gene is a fructose transporter responsible for fructose uptake by the small intestine. The encoded protein also is necessary for the increase in blood pressure due to high dietary fructose consumption. [provided by RefSeq, Jun 2016]

SLC2A5 基因产物(5)

mRNA	Protein	Name
NM_001135585.2	NP_001129057.1	solute carrier family 2, facilitated glucose transporter member 5 isoform 2
NM_001328619.2	NP_001315548.1	solute carrier family 2, facilitated glucose transporter member 5 isoform 1
NM_001328620.2	NP_001315549.1	solute carrier family 2, facilitated glucose transporter member 5 isoform 3
NM_001328621.2	NP_001315550.1	solute carrier family 2, facilitated glucose transporter member 5 isoform 4
NM_003039.3	NP_003030.1	solute carrier family 2, facilitated glucose transporter member 5 isoform 1

基因本体论

分子功能
生物过程
细胞组分

分子功能 GO 注释	逻辑证据	参考文献	来源
enables fructose transmembrane transporter activity	IDA IDA: 通过直接分析推断	8333543	GOA
enables protein binding	IPI IPI: 通过物理相互作用推断	32296183	GOA

生物过程 GO 注释	逻辑证据	参考文献	来源
involved in fructose import across plasma membrane	IDA IDA: 通过直接分析推断	8333543	GOA
involved in fructose transmembrane transport	IDA IDA: 通过直接分析推断	28083649	GOA

细胞组分 GO 注释	逻辑证据	参考文献	来源
located in plasma membrane	IDA IDA: 通过直接分析推断	8333543	GOA

EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

SLC2A5 蛋白结构

Sugar_tr

0
100
200
300
400
501 a.a.

蛋白主名

其他名称

solute carrier family 2, facilitated glucose transporter member 5

glucose transporter type 5, small intestine

SLC2A5 蛋白互作信息

分类	蛋白名称	蛋白编号	互作蛋白	互作蛋白种属	互作蛋白编号	实验方法	参考文献
种属内	SLC2A5	P22732	TMEM237	Homo sapiens	Q96Q45-2	Y2H Prey Pooling	32296183
种属内	SLC2A5	P22732	TMEM237	Homo sapiens	Q96Q45-2	Validated Y2H	32296183
种属内	SLC2A5	P22732	TMEM237	Homo sapiens	Q96Q45-2	Y2H Array	32296183
种属内	SLC2A5	P22732	ARL13B	Homo sapiens	Q3SXY8	Y2H Prey Pooling	32296183
种属内	SLC2A5	P22732	ARL13B	Homo sapiens	Q3SXY8	Validated Y2H	32296183
种属内	SLC2A5	P22732	ARL13B	Homo sapiens	Q3SXY8	Y2H Array	32296183
种属内	SLC2A5	P22732	SCN3B	Homo sapiens	Q9NY72	Y2H Prey Pooling	32296183
种属内	SLC2A5	P22732	SCN3B	Homo sapiens	Q9NY72	Validated Y2H	32296183
种属内	SLC2A5	P22732	SCN3B	Homo sapiens	Q9NY72	Y2H Array	32296183
种属内	SLC2A5	P22732	FCRL3	Homo sapiens	Q96P31-6	Y2H Array	32296183
种属内	SLC2A5	P22732	FCRL3	Homo sapiens	Q96P31-6	Validated Y2H	32296183
种属内	SLC2A5	P22732	FCRL3	Homo sapiens	Q96P31-6	Y2H Prey Pooling	32296183
种属内	SLC2A5	P22732	EVI2B	Homo sapiens	P34910-2	Validated Y2H	32296183
种属内	SLC2A5	P22732	EVI2B	Homo sapiens	P34910-2	Y2H Prey Pooling	32296183
种属内	SLC2A5	P22732	EVI2B	Homo sapiens	P34910-2	Y2H Array	32296183
种属内	SLC2A5	P22732	TMEM130	Homo sapiens	Q8N3G9	Validated Y2H	32296183
种属内	SLC2A5	P22732	TMEM130	Homo sapiens	Q8N3G9	Y2H Array	32296183
种属内	SLC2A5	P22732	PAGE1	Homo sapiens	O75459	Y2H Prey Pooling	32296183
种属内	SLC2A5	P22732	PAGE1	Homo sapiens	O75459	Y2H Array	32296183
种属内	SLC2A5	P22732	COMT	Homo sapiens	P21964	Y2H Prey Pooling	32296183
种属内	SLC2A5	P22732	COMT	Homo sapiens	P21964	Y2H Array	32296183
种属内	SLC2A5	P22732	ATP6V0B	Homo sapiens	Q99437	Y2H Prey Pooling	32296183
种属内	SLC2A5	P22732	ATP6V0B	Homo sapiens	Q99437	Validated Y2H	32296183
种属内	SLC2A5	P22732	ATP6V0B	Homo sapiens	Q99437	Y2H Array	32296183
种属内	SLC2A5	P22732	MGST3	Homo sapiens	O14880	Y2H Prey Pooling	32296183
种属内	SLC2A5	P22732	MGST3	Homo sapiens	O14880	Y2H Array	32296183
种属内	SLC2A5	P22732	MTERF3	Homo sapiens	Q96E29	Validated Y2H	32296183
种属内	SLC2A5	P22732	MTERF3	Homo sapiens	Q96E29	Y2H Prey Pooling	32296183
种属内	SLC2A5	P22732	MTERF3	Homo sapiens	Q96E29	Y2H Array	32296183

种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称

别名

Fructosuria, Essential

Essential Fructosuria	Ketohexokinase Deficiency
Fructosuria	Hepatic Fructokinase Deficiency
Fructokinase Deficiency	FRUCT
Deficiency Of Fructokinase

Lactase Deficiency, Congenital

Congenital Lactase Deficiency	Disaccharide Intolerance Ii
Congenital Alactasia	Congenital Alactasia Syndrome
Congenital Lactose Intolerance	Congenital Lactose Malabsorption
Hereditary Alactasia	Alactasia, Congenital
Cld	COLACD
Disaccharide Intolerance Type 2	Cld - [Congenital Lactase Deficiency]
Disaccharide Intolerance 2	Lactose Intolerance Of Newborn
Hereditary Lactase Deficiency

Osmotic Diarrhea

Lung Acinar Adenocarcinoma

Acinar Adenocarcinoma Of The Lung

Fructose Intolerance, Hereditary

Hereditary Fructose Intolerance	Fructose Intolerance
Fructose-1-Phosphate Aldolase Deficiency	Fructose-1,6-Bisphosphate Aldolase B Deficiency
Aldolase B Deficiency	Fructosemia
Aldob Deficiency	Hereditary Fructose Intolerance Syndrome
HFI	Fructosaemia
Hereditary Fructose-1-Phosphate Aldolase Deficiency	Fructose Aldolase B Deficiency
Fructose-1,6-Biphosphate Aldolase Deficiency	Hereditary Fructosemia
Fructosemia, Hereditary	Hereditary Fructosaemia
Fructose-Biphosphate Aldolase B Deficiency	Fructose Intolerance Of Newborn
Aldb - [Aldolase B] Deficiency	Deficiency Of Fructose-Bisphosphate Aldolase

Sucrase-Isomaltase Deficiency, Congenital

Congenital Sucrase-Isomaltase Deficiency	CSID
Si Deficiency	Congenital Sucrose Intolerance
Disaccharide Intolerance	Sucrase-Isomaltase Deficiency
Disaccharide Intolerance I	Congenital Sucrose-Isomaltose Malabsorption
Sucrose-Isomaltose Malabsorption, Congenital	Sucrose Intolerance, Congenital
Congenital Sucrase-Isomaltose Malabsorption	Congenital Sucrose-Isomaltase Malabsorption
Disaccharide Intolerance, 1	Sucrose Intolerance Congenital
Sucrose-Isomaltase Malabsorption, Congenital	Disaccharidase Deficiency
Invertase Deficiency	Sucrase-Alpha-Dextrinase Deficiency
Disaccharide Intolerance Type I	Csid - [Congenital Sucrase-Isomaltase Deficiency]
Sucrose Intolerance Of Newborn	Sucrose Intolerance
Sucrase Deficiency	Disaccharide Malabsorption
Intestinal Disaccharidase Deficiency

Lactose Intolerance

Lactose Malabsorption	Lm - Lactose Malabsorption
Alactasia	Dairy Product Intolerance
Hypolactasia	Milk Sugar Intolerance
Cow Milk Enteropathy	Intolerance Or Malabsorption Of Lactose
Lm - [Lactose Malabsorption]	Milk Intolerance

疾病名称	别名
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Cat. No.	产品名	作用方式	纯度	是否罕见病
HY-RS13174	SLC2A5 Human Pre-designed siRNA Set A	Pre-designed Sets	/	否

直系同源

种属	基因名	来源	基因 ID
Rattus norvegicus	SLC2A5	RGD	RGD:68328
Mus musculus	SLC2A5	MGD	MGI:1928369
Macaca mulatta	SLC2A5	VGNC	VGNC:77450
Others	SLC2A5	NCBI

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站点地图隐私声明

沪ICP备15051369号-4

上海工商

沪公网安备31011502019417

沪(浦)应急管危经许[2021]201709(QFYS)

营业执照（三证合一）

SLC2A5 - solute carrier family 2 member 5 Gene

关于 SLC2A5

功能概要

SLC2A5 基因产物(5)

SLC2A5 蛋白结构

SLC2A5 蛋白互作信息

关联疾病

直系同源

热门区域

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SLC2A5 - solute carrier family 2 member 5 Gene

关于 SLC2A5

功能概要

SLC2A5 基因产物(5)

SLC2A5 蛋白结构

SLC2A5 蛋白互作信息

关联疾病

相关产品

直系同源

热门区域

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B

C

F

G

H

J

L

N

Q

S

T

X

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Z