ATP6V0B - ATPase H+ transporting V0 subunit b Gene

中文名称：ATPase H+ 转运 V0 亚基 b

种属: Homo sapiens

同用名: ATP6F; HATPL; VMA16

关于 ATP6V0B

功能概要

该基因编码液泡 ATP 酶 (V-ATPase) 的 V0 结构域的一部分，这是一种介导真核细胞内细胞器酸化的多亚基酶。这种酶的活性对于蛋白质分选、酶原激活、受体介导的内吞作用和突触小泡质子梯度生成等多种过程是必需的。可变剪接导致多个转录本变体。[RefSeq 提供，2014 年 6 月]

This gene encodes a portion of the V0 domain of vacuolar ATPase (V-ATPase), a multisubunit Enzyme that mediates acidification of eukaryotic intracellular organelles. Activity of this Enzyme is necessary for such varied processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2014]