2. Gene
  3. NRM - nurim Gene

NRM - nurim Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：努里姆

种属: Homo sapiens

同用名: NRM29

基因 ID: 11270 | 基因类型: protein coding

关于 NRM

Cytogenetic location: 6p21.33 Genomic coordinates (GRCh38): 6:30,688,049-30,691,420 (from NCBI)

This gene has 9 transcripts (splice variants), 1 gene allele and 182 orthologues. Ubiquitous expression in skin (RPKM 5.3), bone marrow (RPKM 5.1) and 25 other tissues.

功能概要

由该基因编码的蛋白质包含跨膜结构域，位于内核膜内，与细胞核紧密相关。该蛋白质与异戊二烯半胱氨酸羧甲基转移酶具有同源性。可变剪接导致编码不同蛋白质亚型的多个转录变体。[RefSeq 提供，2012 年 7 月]

The protein encoded by this gene contains transmembrane domains and resides within the inner nuclear membrane, where it is tightly associated with the nucleus. This protein shares homology with isoprenylcysteine carboxymethyltransferase Enzymes. Alternative splicing results in multiple transcript variants that encode different protein isoforms. [provided by RefSeq, Jul 2012]

NRM 基因产物(6)

mRNA Protein Name
NM_001270707.2 NP_001257636.1 nurim isoform 2
NM_001270708.2 NP_001257637.1 nurim isoform 3
NM_001270709.2 NP_001257638.1 nurim isoform 4
NM_001270710.2 NP_001257639.1 nurim isoform 5
NM_001384369.1 NP_001371298.1 nurim isoform 1
NM_007243.3 NP_009174.1 nurim isoform 1
基因本体论
  • 分子功能
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
25416956 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in nuclear envelope IDA
IDA: 通过直接分析推断
10402458 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

NRM 蛋白结构

NnrU

NnrU: NnrU protein (69 - 201)

  • 0
  • 100
  • 200
  • 262 a.a.
蛋白主名 其他名称

nurim

nuclear rim protein

关联疾病

疾病名称 别名
Amyotrophic Lateral Sclerosis 20

Amyotrophic Lateral Sclerosis Type 20

ALS20

Sclerosis, Lateral, Amyotrophic, Type 20
Amyotrophic Lateral Sclerosis Type 5

Amyotrophic Lateral Sclerosis 5

Als5
Amyotrophic Lateral Sclerosis 10 With Or Without Frontotemporal Dementia

Amyotrophic Lateral Sclerosis Type 10

ALS10

Amyotrophic Lateral Sclerosis 10, With Or Without Ftd

Frontotemporal Lobar Degeneration, Tardbp-Related

Amyotrophic Lateral Sclerosis 10

Amyotrophic Lateral Sclerosis 10, With Or Without Frontotemporal Dementia

Tardbp-Related Frontotemporal Lobar Degeneration With Tdp43 Inclusions

Amyotrophic Lateral Sclerosis 10 With Or Without Frontotemporal Dementia And With Tdp43 Inclusions

Sclerosis, Lateral, Amyotrophic, Type Type 10
Acatalasemia

Acatalasia

Catalase Deficiency

Deficiency Of Catalase

ACATLAS

Takahara'S Disease

Takahara Disease
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (4)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-121404A Muscarine chloride Agonist ≥99.0% 否
HY-107654 Muscarine iodide Agonist ≥97.0% 否
HY-121404 Muscarine Agonist / 否
HY-RS09576 NRM Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Bos taurus NRM VGNC VGNC:49560
Rattus norvegicus NRM RGD RGD:1302966
Macaca mulatta NRM VGNC VGNC:75531
Felis catus NRM VGNC VGNC:68568
Mus musculus NRM MGD MGI:2146855
Others NRM NCBI
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