FRMD3 - FERM domain containing 3 Gene

中文名称：含 FERM 域 3

种属: Homo sapiens

同用名: 4.1O; P410; EPB41LO; EPB41L4O

关于 FRMD3

功能概要

由该基因编码的蛋白质是一种主要存在于卵巢中的单程膜蛋白。红细胞中的一种类似蛋白质有助于确定红细胞的形状，但编码蛋白质的功能尚未确定。有证据表明这是一种肿瘤抑制基因，也有证据表明该基因的缺陷与 1 型糖尿病患者对糖尿病肾病的易感性有关。已发现该基因编码不同亚型的几种转录变体。[RefSeq 提供，2011 年 10 月]

The protein encoded by this gene is a single pass membrane protein primarily found in ovaries. A similar protein in erythrocytes helps determine the shape of red blood cells, but the function of the encoded protein has not been determined. There is some evidence that this is a tumor suppressor gene, and there is also evidence linking defects in this gene to susceptibility to diabetic nephropathy in type 1 diabetes. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]