2. Gene
  3. SERP1 - stress associated endoplasmic reticulum protein 1 Gene

SERP1 - stress associated endoplasmic reticulum protein 1 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：应激相关内质网蛋白 1

种属: Homo sapiens

同用名: RAMP4

基因 ID: 27230 | 基因类型: protein coding

关于 SERP1

Cytogenetic location: 3q25.1 Genomic coordinates (GRCh38): 3:150,541,998-150,546,496 (from NCBI)

This gene has 8 transcripts (splice variants), 191 orthologues and 1 paralogue. Ubiquitous expression in thyroid (RPKM 68.2), prostate (RPKM 46.3) and 25 other tissues.

功能概要

预计参与内质网未折叠蛋白反应和蛋白糖基化。预计在多个过程的上游或内部起作用，包括多细胞生物老化；器官生长的积极调节；肽激素分泌的正调节作用。位于细胞质微管中。 [由基因组资源联盟提供，2022 年 4 月]

Predicted to be involved in endoplasmic reticulum unfolded protein response and protein glycosylation. Predicted to act upstream of or within several processes, including multicellular organism aging; positive regulation of organ growth; and positive regulation of peptide hormone secretion. Located in cytoplasmic microtubule. [provided by Alliance of Genome Resources, Apr 2022]

SERP1 基因产物(1)

mRNA Protein Name
NM_014445.4 NP_055260.1 stress-associated endoplasmic reticulum protein 1
基因本体论
  • 分子功能
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
25416956 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cytoplasmic microtubule IDA
IDA: 通过直接分析推断
23264731 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

SERP1 蛋白结构

RAMP4

RAMP4: Ribosome associated membrane protein RAMP4 (1 - 64)

  • 0
  • 66 a.a.
蛋白主名 其他名称

stress-associated endoplasmic reticulum protein 1

ribosome associated membrane protein 4

关联疾病

疾病名称 别名
Arachnoiditis

Spinal Arachnoiditis

Adhesive Arachnoiditis

Chronic Arachnoiditis

Familial Spinal Arachnoiditis

Arachnitis

Arachnoid Inflammation
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (2)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS12694 SERP1 Human Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS12727 SERPING1 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Bos taurus SERP1 VGNC VGNC:34464
Felis catus SERP1 VGNC VGNC:102840
Macaca mulatta SERP1 VGNC VGNC:77175
Rattus norvegicus SERP1 RGD RGD:620790
Mus musculus SERP1 MGD MGI:92638
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