2. Gene
  3. SEC11C - SEC11 homolog C, signal peptidase complex subunit Gene

SEC11C - SEC11 homolog C, signal peptidase complex subunit Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：SEC11 同系物 C，信号肽酶复合亚基

种属: Homo sapiens

同用名: SPC21; SPCS4C; SEC11L3

基因 ID: 90701 | 基因类型: protein coding

关于 SEC11C

This gene has 8 transcripts (splice variants), 135 orthologues and 1 paralogue. Ubiquitous expression in prostate (RPKM 109.5), thyroid (RPKM 61.5) and 25 other tissues.

功能概要

预测启用肽酶活性。预测参与信号肽加工。预测位于内质网膜。预计是信号肽酶复合物的一部分。 [由基因组资源联盟提供，2022 年 4 月]

Predicted to enable peptidase activity. Predicted to be involved in signal peptide processing. Predicted to be located in endoplasmic reticulum membrane. Predicted to be part of signal peptidase complex. [provided by Alliance of Genome Resources, Apr 2022]

SEC11C 基因产物(2)

mRNA Protein Name
NM_001307941.2 NP_001294870.1 signal peptidase complex catalytic subunit SEC11C isoform 2
NM_033280.4 NP_150596.1 signal peptidase complex catalytic subunit SEC11C isoform 1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
28514442 GOA
enables serine-type endopeptidase activity IDA
IDA: 通过直接分析推断
34388369 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in signal peptide processing IDA
IDA: 通过直接分析推断
34388369 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in endoplasmic reticulum membrane IDA
IDA: 通过直接分析推断
34388369 GOA
part of signal peptidase complex IDA
IDA: 通过直接分析推断
34388369 GOA
part of signal peptidase complex IPI
IPI: 通过物理相互作用推断
34388369 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

SEC11C 蛋白结构

Peptidase_S24

Peptidase_S24: Peptidase S24-like (64 - 115)

  • 0
  • 100
  • 192 a.a.
蛋白主名 其他名称

signal peptidase complex catalytic subunit SEC11C

SEC11-like 3

SEC11C 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
Intra SEC11C Q9BY50 SERP1 Homo sapiens Q9Y6X1
Validated Y2H
32296183
Intra SEC11C Q9BY50 VAPA Homo sapiens Q9P0L0
Validated Y2H
32296183
Intra SEC11C Q9BY50 TMEM128 Homo sapiens Q5BJH2-2
Y2H Array
32296183
Intra SEC11C Q9BY50 MFF Homo sapiens Q9GZY8-5
Validated Y2H
32296183
Intra SEC11C Q9BY50 TREX1 Homo sapiens Q9NSU2-1
Validated Y2H
32296183
Intra SEC11C Q9BY50 SPCS3 Homo sapiens P61009
3D-EM
34388369
Intra SEC11C Q9BY50 SPCS3 Homo sapiens P61009
Anti Tag CoIP
34388369
Intra SEC11C Q9BY50 SPCS3 Homo sapiens P61009
Anti Tag CoIP
33961781
Intra SEC11C Q9BY50 SPCS3 Homo sapiens P61009
Anti Tag CoIP
28514442
Intra SEC11C Q9BY50 SPCS3 Homo sapiens P61009
Crosslink
34388369
Intra SEC11C Q9BY50 SPCS3 Homo sapiens P61009
SLCA
34388369
Intra SEC11C Q9BY50 UBE2J1 Homo sapiens Q9Y385
Validated Y2H
32296183
种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称 别名
Malignant Inflammatory Fibrous Histiocytoma

Inflammatory Mfh

Xanthosarcoma
Malignant Iris Melanoma

Malignant Melanoma Of Iris

Melanoma Of The Iris
X-Linked Intellectual Disability-Psychosis-Macroorchidism Syndrome

Mrxs13

Lindsay-Burn Syndrome

Ppm-X

Ppm-X Syndrome

Mental Retardation With Psychosis, Pyramidal Signs, And Macroorchidism

Mental Retardation, X-Linked, Syndromic 13

X-Linked Mental Retardation 79

X-Linked Mental Retardation With Spasticity

Intellectual Deficit, X-Linked - Psychosis - Macroorchidism

Intellectual Disability Psychosis Macroorchidism

Intellectual Disability With Psychosis, Pyramidal Signs, And Macroorchidism

Intellectual Disability, X-Linked, Syndromic 13

Ppmx

X-Linked Mental Retardation, Syndromic 13
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS12604 SEC11C Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Rattus norvegicus SEC11C RGD RGD:628665
Canis familiaris SEC11C VGNC VGNC:45961
Macaca mulatta SEC11C VGNC VGNC:77295
Bos taurus SEC11C VGNC VGNC:34402
Mus musculus SEC11C MGD MGI:1913536
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